about
Thrombocytopenia caused by passive transfusion of anti-glycoprotein Ia/IIa alloantibody (anti-HPA-5b).Inherited disorders of platelet alpha-granules.Laboratory testing for heparin-induced thrombocytopenia is inconsistent in North America: a survey of North American specialized coagulation laboratories.An evaluation of methods for determining reference intervals for light transmission platelet aggregation tests on samples with normal or reduced platelet counts.Characterization and localization of the Gova/b alloantigens to the glycosylphosphatidylinositol-anchored protein CDw109 on human platelets.Sera from patients with heparin-induced thrombocytopenia generate platelet-derived microparticles with procoagulant activity: an explanation for the thrombotic complications of heparin-induced thrombocytopenia.Immunoglobulin G from patients with heparin-induced thrombocytopenia binds to a complex of heparin and platelet factor 4.The prenatal identification of fetal compatibility in neonatal alloimmune thrombocytopenia using amniotic fluid and variable number of tandem repeat (VNTR) analysis.Persons with Quebec platelet disorder have a tandem duplication of PLAU, the urokinase plasminogen activator gene.Identification of the MMRN1 binding region within the C2 domain of human factor V.An autosomal dominant, qualitative platelet disorder associated with multimerin deficiency, abnormalities in platelet factor V, thrombospondin, von Willebrand factor, and fibrinogen and an epinephrine aggregation defect.Studies of multimerin in human endothelial cells.The duplication mutation of Quebec platelet disorder dysregulates PLAU, but not C10orf55, selectively increasing production of normal PLAU transcripts by megakaryocytes but not granulocytes.Congenital platelet disorders: overview of their mechanisms, diagnostic evaluation and treatment.Platelet function testing: quality assurance.Location of the multimerin 1 binding site in coagulation factor V: an update.Development of North American consensus guidelines for medical laboratories that perform and interpret platelet function testing using light transmission aggregometry.Diagnostic evaluation of platelet function disorders.Clinician investigator training in Canada: a review.Improving blood disorder diagnosis: reflections on the challenges.Laboratory testing for bleeding disorders: strategic uses of high and low-yield tests.Recommendations for the Standardization of Light Transmission Aggregometry: A Consensus of the Working Party from the Platelet Physiology Subcommittee of SSC/ISTH.Technological advances in diagnostic testing for von Willebrand disease: new approaches and challenges.Results of an external proficiency testing exercise on platelet dense-granule deficiency testing by whole mount electron microscopy.Quebec platelet disorder is linked to the urokinase plasminogen activator gene (PLAU) and increases expression of the linked allele in megakaryocytesProtein C assay performance: an analysis of North American specialized coagulation laboratory association proficiency testing results.Results of a worldwide survey on the assessment of platelet function by light transmission aggregometry: a report from the platelet physiology subcommittee of the SSC of the ISTH.External quality assessment of platelet disorder investigations: results of international surveys on diagnostic tests for dense granule deficiency and platelet aggregometry interpretation.Loss of factor VIII activity during storage in PVC containers due to adsorption.Thrombopoietin levels in Quebec platelet disorder-Implications for the mechanism of thrombocytopenia.Assembly and evaluation of an inventory of guidelines that are available to support clinical hematology laboratory practice.Mice with deleted multimerin 1 and alpha-synuclein genes have impaired platelet adhesion and impaired thrombus formation that is corrected by multimerin 1Multimerin 1 binds factor V and activated factor V with high affinity and inhibits thrombin generationFactor V is complexed with multimerin in resting platelet lysates and colocalizes with multimerin in platelet alpha-granulesAnalyses of cellular multimerin 1 receptors: in vitro evidence of binding mediated by alphaIIbbeta3 and alphavbeta3Insights into abnormal hemostasis in the Quebec platelet disorder from analyses of clot lysis.Variability in clinical laboratory practice in testing for disorders of platelet function: results of two surveys of the North American Specialized Coagulation Laboratory Association.Diagnosis of suspected inherited platelet function disorders: results of a worldwide survey.A prospective cohort study of light transmission platelet aggregometry for bleeding disorders: is testing native platelet-rich plasma non-inferior to testing platelet count adjusted samples?Factor XIII Assays and associated problems for laboratory diagnosis of factor XIII deficiency: an analysis of International Proficiency testing results.
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description
Forscher
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chercheur
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investigador
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researcher
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ricercatore
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研究者
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name
C P Hayward
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C P Hayward
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C P Hayward
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C P Hayward
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C P Hayward
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C P Hayward
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C P Hayward
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C P Hayward
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C P Hayward
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C P Hayward
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C P Hayward
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C P Hayward
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P31
P496
0000-0002-2843-0817