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Cytotoxicity and mutagenicity of fluoxetine hydrochloride (Prozac), with or without vitamins A and C, in plant and animal model systems.Evaluation of the antimutagenic activity and mode of action of the fructooligosaccharide inulin in the meristematic cells of Allium cepa culture.Mutagenic and antimutagenic effects of aqueous extract of rosemary (Rosmarinus officinalis L.) on meristematic cells of Allium cepa.Analysis of the genotoxic potential of low concentrations of Malathion on the Allium cepa cells and rat hepatoma tissue culture.Antiviral activity of aqueous and ethanol extracts and of an isolated polysaccharide from Agaricus brasiliensis against poliovirus type 1.Genotoxic evaluation of an industrial effluent from an oil refinery using plant and animal bioassaysEvaluation of the cytotoxicity, mutagenicity and antimutagenicity of a natural antidepressant, Hypericum perforatum L. (St. John's wort), on vegetal and animal test systems.Chemoprotective activity of the isoflavones, genistein and daidzein on mutagenicity induced by direct and indirect mutagens in cultured HTC cellsbeta-Glucans in promoting health: prevention against mutation and cancer.Genistein at maximal physiologic serum levels induces G0/G1 arrest in MCF-7 and HB4a cells, but not apoptosis.Evaluation of the effects of nicorandil and its molecular precursor (without radical NO) on proliferation and apoptosis of 786-cellCytotoxic, biochemical and genotoxic effects of biodiesel produced by different routes on ZFL cell line.Effects of genistein and daidzein on cell proliferation kinetics in HT29 colon cancer cells: the expression of CTNNBIP1 (β-catenin), APC (adenomatous polyposis coli) and BIRC5 (survivin).Genotoxic evaluation of the antimalarial drugs artemisinin and artesunate in human HepG2 cells and effects on CASP3 and SOD1 gene expressions.Evaluation of the genotoxic and anti-genotoxic activities of silybin in human hepatoma cells (HepG2).Effects of chlorophyllin on replication of poliovirus and bovine herpesvirus in vitro.Protective effects of beta-glucan extracted from barley against benzo[a]pyrene-induced DNA damage in hepatic cell HepG2.Genotoxic, mutagenic and cytotoxic effects of the commercial dye CI Disperse Blue 291 in the human hepatic cell line HepG2.Protective effect of beta-glucan extracted from Saccharomyces cerevisiae, against DNA damage and cytotoxicity in wild-type (k1) and repair-deficient (xrs5) CHO cells.Anti-clastogenic effect of beta-glucan extracted from barley towards chemically induced DNA damage in rodent cells.Evaluation of antimutagenic activity and mechanisms of action of beta-glucan from barley, in CHO-k1 and HTC cell lines using the micronucleus test.Antigenotoxicity of Agaricus blazei mushroom organic and aqueous extracts in chromosomal aberration and cytokinesis block micronucleus assays in CHO-k1 and HTC cells.Chlorophyllin protects HEp-2 cells from nuclear fragmentation induced by poliovirus.Variation of the antimutagenicity effects of water extracts of Agaricus blazei Murrill in vitro.Investigation of genotoxic and antigenotoxic activities of chlorophylls and chlorophyllin in cultured V79 cells.Compounds used to produce cloned animals are genotoxic and mutagenic in mammalian assays in vitro and in vivo.Antiproliferative activity of goniothalamin enantiomers involves DNA damage, cell cycle arrest and apoptosis induction in MCF-7 and HB4a cells.Antimutagenic effects of the mushroom Agaricus blazei Murrill extracts on V79 cells.Pre-treatment with glutamine reduces genetic damage due to cancer treatment with cisplatin.The azo dyes Disperse Red 1 and Disperse Orange 1 increase the micronuclei frequencies in human lymphocytes and in HepG2 cells.Anticlastogenicity of chlorophyllin in the different cell cycle phases in cultured mammalian cells.Possible modulating actions of plant extracts on the chromosome breaking activity of MMC and Ara-C in human lymphocytes in vitro.Plasma malondialdehyde levels and CXCR4 expression in peripheral blood cells of breast cancer patients.Cytotoxicity, genotoxicity and antimutagenicity of hexane extracts of Agaricus blazei determined in vitro by the comet assay and CHO/HGPRT gene mutation assay.6-Dimethylaminopurine and cyclohexamide are mutagenic and alter reproductive performance and intrauterine development in vivo.Chlorination treatment of aqueous samples reduces, but does not eliminate, the mutagenic effect of the azo dyes Disperse Red 1, Disperse Red 13 and Disperse Orange 1.Effects of sulfated and non-sulfated β-glucan extracted from Agaricus brasiliensis in breast adenocarcinoma cells - MCF-7.Activity of selenium on cell proliferation, cytotoxicity, and apoptosis and on the expression of CASP9, BCL-XL and APC in intestinal adenocarcinoma cells.Effects of β-glucan extracted from Agaricus blazei on the expression of ERCC5, CASP9, and CYP1A1 genes and metabolic profile in HepG2 cells.CXCL12 rs1801157 polymorphism and expression in peripheral blood from breast cancer patients.
P50
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P50
description
Forscher
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investigador
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wetenschapper
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研究者
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M S Mantovani
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M S Mantovani
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M S Mantovani
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M S Mantovani
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M S Mantovani
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M S Mantovani
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M S Mantovani
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M S Mantovani
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M S Mantovani
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M S Mantovani
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M S Mantovani
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M S Mantovani
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P31
P496
0000-0001-5268-6508