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Preferential binding of a G-quadruplex ligand to human chromosome ends.Age-related neurogenesis decline in the subventricular zone is associated with specific cell cycle regulation changes in activated neural stem cellsIn vivo importance of homologous recombination DNA repair for mouse neural stem and progenitor cellsClinical relevance of tumor cells with stem-like properties in pediatric brain tumors.Neural stem cells from mouse forebrain are contained in a population distinct from the 'side population'.Targeting human telomerase for cancer therapeutics.Cellular and behavioral effects of cranial irradiation of the subventricular zone in adult mice.PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways.ATR contributes to telomere maintenance in human cellsAssessing cell cycle progression of neural stem and progenitor cells in the mouse developing brain after genotoxic stress.Disruption of Adult Neurogenesis in the Olfactory Bulb Affects Social Interaction but not Maternal BehaviorQuiescent neural stem cells exit dormancy upon alteration of GABAAR signaling following radiation damage.A preclinical mouse model of glioma with an alternative mechanism of telomere maintenance (ALT).Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors.Characterization of human immunodeficiency virus type 1 p17 matrix protein motifs associated with mother-to-child transmission.Lack of a p21waf1/cip -dependent G1/S checkpoint in neural stem and progenitor cells after DNA damage in vivo.The prion protein is critical for DNA repair and cell survival after genotoxic stress.Radiation-induced upregulation of telomerase activity escapes PI3-kinase inhibition in two malignant glioma cell lines.Hedgehog Controls Quiescence and Activation of Neural Stem Cells in the Adult Ventricular-Subventricular Zone.Rad51 and DNA-PKcs are involved in the generation of specific telomere aberrations induced by the quadruplex ligand 360A that impair mitotic cell progression and lead to cell death.Long-term controlled immortalization of a primate hepatic progenitor cell line after Simian virus 40 T-Antigen gene transfer.Antibody-dependent cellular cytotoxicity and neutralization of human immunodeficiency virus type 1 by high affinity cross-linking of gp41 to human macrophage Fc IgG receptor using bispecific antibody.Role of ATM in the telomere response to the G-quadruplex ligand 360A.Opposite effects of GCN5 and PCAF knockdowns on the alternative mechanism of telomere maintenance.c-Fos importance for brain development.Cell Sorting of Neural Stem and Progenitor Cells from the Adult Mouse Subventricular Zone and Live-imaging of their Cell Cycle Dynamics.Brain development is impaired in c-fos -/- mice.[Astrocytes and lentivirus infection in an experimental models of macaque infected with SIVmac251]TGFβ lengthens the G1 phase of stem cells in aged mouse brain.Astrocyte gene expression in experimental mouse scrapie.Different DNA-PKcs functions in the repair of radiation-induced and spontaneous DSBs within interstitial telomeric sequences.Alternative lengthening of telomeres in human glioma stem cells.Mechanisms of downmodulation and release of tumour necrosis factor receptor induced by human immunodeficiency virus type 1 in human monocytes.Macrophage inflammatory protein-1 alpha mRNA expression in mononuclear cells from different tissues during acute simian immunodeficiency virus strain mac251 infection of macaques.In vitro infection of human macrophages with human T-cell leukemia virus type 1.Inactivation of human immunodeficiency virus during human growth hormone production.Isolation of Neural Stem and Progenitor Cells from the Adult Brain and Live Imaging of Their Cell Cycle with the FUCCI System.[TGFβ, a troublemaker in the adult neural stem cell niche].Radiation-induced mitotic catastrophe in PARG-deficient cells.Variation of radiation-sensitivity of neural stem and progenitor cell populations within the developing mouse brain.
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Forscher
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Francois Boussin
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Francois Boussin
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P108
P108
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0000-0003-3778-4403