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Pressure (< or=4 ATA) increases membrane conductance and firing rate in the rat solitary complex.Somatic vs. dendritic responses to hypercapnia in chemosensitive locus coeruleus neurons from neonatal rats.Hyperoxic stimulation of synchronous orthodromic activity and induction of neural plasticity does not require changes in excitatory synaptic transmission.Development and testing of hyperbaric atomic force microscopy (AFM) and fluorescence microscopy for biological applications.Gap junctions in CO(2)-chemoreception and respiratory control.Peripheral chemoreceptors tune inspiratory drive via tonic expiratory neuron hubs in the medullary ventral respiratory column network.Substance P differentially modulates firing rate of solitary complex (SC) neurons from control and chronic hypoxia-adapted adult ratsHyperoxia, reactive oxygen species, and hyperventilation: oxygen sensitivity of brain stem neurons.Functional connectivity in raphé-pontomedullary circuits supports active suppression of breathing during hypocapnic apnea.Characterization of the chemosensitive response of individual solitary complex neurons from adult ratsChronic hypoxia suppresses the CO2 response of solitary complex (SC) neurons from rats.pH regulating transporters in neurons from various chemosensitive brainstem regions in neonatal ratsThe caudal solitary complex is a site of central CO(2) chemoreception and integration of multiple systems that regulate expired CO(2).Theory of gastric CO2 ventilation and its control during respiratory acidosis: implications for central chemosensitivity, pH regulation, and diseases causing chronic CO2 retention.Normobaric hyperoxia stimulates superoxide and nitric oxide production in the caudal solitary complex of rat brain slices.Characterization of cardiovascular reflexes evoked by airway stimulation with allylisothiocyanate, capsaicin, and ATP in Sprague-Dawley rats.Therapeutic ketosis with ketone ester delays central nervous system oxygen toxicity seizures in rats.Development of in vivo ventilatory and single chemosensitive neuron responses to hypercapnia in rats.Acute hypercapnic hyperoxia stimulates reactive species production in the caudal solitary complex of rat brain slices but does not induce oxidative stress.Intrinsic chemosensitivity of individual nucleus tractus solitarius (NTS) and locus coeruleus (LC) neurons from neonatal rats.Carotid chemoreceptors tune breathing via multipath routing: Reticular chain and loop operations supported by parallel spike train correlations.Metabolic acidosis inhibits hypothalamic warm-sensitive receptors: a potential causative factor in heat stroke.Cell-cell coupling between CO2-excited neurons in the dorsal medulla oblongata.A fluorescence technique to measure intracellular pH of single neurons in brainstem slices.In appreciation: Charles M. Tipton and the history of physiology.Delaying latency to hyperbaric oxygen-induced CNS oxygen toxicity seizures by combinations of exogenous ketone supplementsDepolarization and stimulation of neurons in nucleus tractus solitarii by carbon dioxide does not require chemical synaptic inputThe chemosensitive response of neurons from the locus coeruleus (LC) to hypercapnic acidosis with clamped intracellular pHNormobaric hyperoxia (95% O₂) stimulates CO₂-sensitive and CO₂-insensitive neurons in the caudal solitary complex of rat medullary tissue slices maintained in 40% O₂CNS function and dysfunction during exposure to hyperbaric oxygen in operational and clinical settingsRelationships between three and twelve month outcomes in children enrolled in the therapeutic hypothermia after pediatric cardiac arrest trialsMachine Learning in Medicine
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P50
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