about
Protein tyrosine phosphatases and breast cancer.Reconstruction and signal propagation analysis of the Syk signaling network in breast cancer cells.Catalytically inactive human cathepsin D triggers fibroblast invasive growthExpression of the putative tumor suppressor gene PTPN13/PTPL1 is an independent prognostic marker for overall survival in breast cancer.Semiquantitative reverse transcription-polymerase chain reaction to evaluate the expression patterns of genes involved in the oestrogen pathway.The putative tumor suppressor gene PTPN13/PTPL1 induces apoptosis through insulin receptor substrate-1 dephosphorylation.Effect of prolonged hydroxytamoxifen treatment of MCF-7 cells on mitogen activated kinase cascade.Autocrine growth stimulation of the MCF 7 breast cancer cells by the estrogen-regulated 52 K protein.Membrane targeting of protein tyrosine phosphatase PTPL1 through its FERM domain via binding to phosphatidylinositol 4,5-biphosphate.Anti-growth factor activities of benzothiophenes in human breast cancer cells.High PTPN13 expression in high grade serous ovarian carcinoma is associated with a better patient outcome.Structure, function, regulation and clinical significance of the 52K pro-cathepsin D secreted by breast cancer cells.Mechanisms of 4-hydroxytamoxifen anti-growth factor activity in breast cancer cells: alterations of growth factor receptor binding sites and tyrosine kinase activityCharacterization and properties of two monoclonal antibodies specific for the Mr 52,000 precursor of cathepsin D in human breast cancer cellsTwo-site immunoenzymometric assay for the 52-kDa cathepsin D in cytosols of breast cancer tissuesA two-site immunoenzymometric assay of 52-kDa pro-cathepsin D, and its use in human breast diseasesAssociation between high concentrations of Mr 52,000 cathepsin D and poor prognosis in primary human breast cancerTamoxifen treatment increases the concentration of 52K-cathepsin D and its precursor in breast cancer tissueAntiestrogens increase protein tyrosine phosphatase activity in human breast cancer cellsThe Syk Kinase Promotes Mammary Epithelial Integrity and Inhibits Breast Cancer Invasion by Stabilizing the E-Cadherin/Catenin ComplexPTPN13 induces cell junction stabilization and inhibits mammary tumor invasivenessNetwork Reconstruction and Significant Pathway Extraction Using Phosphoproteomic Data from Cancer Cells
P50
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P50
description
Forscher
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研究者
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G Freiss
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G Freiss
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G Freiss
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G Freiss
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G Freiss
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G Freiss
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G Freiss
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G Freiss
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G Freiss
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G Freiss
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G Freiss
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G Freiss
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P31
P496
0000-0002-1943-0735