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A homozygous mutation in human PRICKLE1 causes an autosomal-recessive progressive myoclonus epilepsy-ataxia syndromeMethods for studying planar cell polarityNaked cuticle targets dishevelled to antagonize Wnt signal transductionAsymmetric distribution of prickle-like 2 reveals an early underlying polarization of vestibular sensory epithelia in the inner earPrickle mediates feedback amplification to generate asymmetric planar cell polarity signalingDifferential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathwaysMyb promotes centriole amplification and later steps of the multiciliogenesis program.Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways.Prickle/spiny-legs isoforms control the polarity of the apical microtubule network in planar cell polarity.Planar cell polarity enables posterior localization of nodal cilia and left-right axis determination during mouse and Xenopus embryogenesis.Understanding biology by reverse engineering the controlThe Drosophila casein kinase Iepsilon/delta Discs overgrown promotes cell survival via activation of DIAP1 expression.prickle modulates microtubule polarity and axonal transport to ameliorate seizures in flies.D2 dopamine receptors colocalize regulator of G-protein signaling 9-2 (RGS9-2) via the RGS9 DEP domain, and RGS9 knock-out mice develop dyskinesias associated with dopamine pathways.A three-tiered mechanism for regulation of planar cell polarity.Multicilin promotes centriole assembly and ciliogenesis during multiciliate cell differentiationA universal analysis tool for the detection of asymmetric signal distribution in microscopic images.Biology by numbers: mathematical modelling in developmental biology.Planar cell polarity signaling: the developing cell's compass.Progress and challenges in understanding planar cell polarity signaling.Dishevelled links basal body docking and orientation in ciliated epithelial cells.Delivering the lateral inhibition punchline: it's all about the timing.Pointing in the right direction: new developments in the field of planar cell polarity.Asymmetric protein localization in planar cell polarity: mechanisms, puzzles, and challenges.Remodeling a tissue: subtraction adds insight.Regulation of PCP by the Fat signaling pathway.Microtubules enable the planar cell polarity of airway cilia.Mathematical modeling of planar cell polarity to understand domineering nonautonomy.GAL4 disrupts a repressing nucleosome during activation of GAL1 transcription in vivo.Basal bodies, kinocilia and planar cell polarity.Wnt Signaling in Chronic Rhinosinusitis with Nasal Polyps.Fidelity in planar cell polarity signalling.Drosophila Rho-associated kinase (Drok) links Frizzled-mediated planar cell polarity signaling to the actin cytoskeleton.FijiWingsPolarity: An open source toolkit for semi-automated detection of cell polarity.Cell shape in proliferating epithelia: a multifaceted problem.Frizzled signaling and the developmental control of cell polarity.A WNTer wonderland in SnowbirdPlanar cell polarity orients airway ciliaVANGL2 regulates luminal epithelial organization and cell turnover in the mammary glandUnique cytochalasin B binding characteristics of the hepatic glucose carrier
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description
researcher
@en
name
J D Axelrod
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J D Axelrod
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J D Axelrod
@en
J D Axelrod
@nl
prefLabel
J D Axelrod
@en
J D Axelrod
@nl
P106
P31
P496
0000-0001-6094-7392