about
Mutations in ABCA12 underlie the severe congenital skin disease harlequin ichthyosis.Pachyonychia congenita cornered: report on the 11th Annual International Pachyonychia Congenita Consortium MeetingMutations in AQP5, encoding a water-channel protein, cause autosomal-dominant diffuse nonepidermolytic palmoplantar keratoderma.Necrobiosis lipoidica: only a minority of patients have diabetes mellitus.iRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier functionExtracellular matrix and keratinocyte migration.Loss-of-function mutations in CAST cause peeling skin, leukonychia, acral punctate keratoses, cheilitis, and knuckle pads.A Novel Fully Humanized 3D Skin Equivalent to Model Early Melanoma Invasion.Cytoskeletal protein Flightless I inhibits apoptosis, enhances tumor cell invasion and promotes cutaneous squamous cell carcinoma progressionHypoxia increases human keratinocyte motility on connective tissue.RNA-seq analysis of host and viral gene expression highlights interaction between varicella zoster virus and keratinocyte differentiation.Connexins in epidermal homeostasis and skin disease.Matrix metalloproteinases and epidermal wound repair.Recent advances in the genetics and management of harlequin ichthyosis.Keratins and skin disease.Laminin-5 inhibits human keratinocyte migration.Suppression of TGFβ and Angiogenesis by Type VII Collagen in Cutaneous SCC.The future of U.K. dermatology translational research through the Oracle of Delphi.Epidermal grafting for wound healing: a review on the harvesting systems, the ultrastructure of the graft and the mechanism of wound healing.Metalloproteinases and Wound Healing.The receptor tyrosine kinase Axl regulates cell-cell adhesion and stemness in cutaneous squamous cell carcinoma.Desmoglein 3 promotes cancer cell migration and invasion by regulating activator protein 1 and protein kinase C-dependent-Ezrin activation.Axl promotes cutaneous squamous cell carcinoma survival through negative regulation of pro-apoptotic Bcl-2 family members.Ultra-deformable liposomes containing bleomycin: in vitro stability and toxicity on human cutaneous keratinocyte cell lines.Molecular cloning of canine bullous pemphigoid antigen 2 cDNA and immunomapping of NC16A domain by canine bullous pemphigoid autoantibodies.Integrin alpha 5 beta 1 expression is required for inhibition of keratinocyte migration by ganglioside GT1b.Hypoxia induces epidermal keratinocyte matrix metalloproteinase-9 secretion via the protein kinase C pathway.Increased invasive behaviour in cutaneous squamous cell carcinoma with loss of basement-membrane type VII collagen.Expanding the Phenotypic Spectrum of Olmsted Syndrome.Phosphorylation of focal adhesion kinase (pp125(FAK)) is increased in human keratinocytes induced to migrate by extracellular matrices.Targeted sequence capture and high-throughput sequencing in the molecular diagnosis of ichthyosis and other skin diseases.The epidermolysis bullosa acquisita antigen (type VII collagen) is present in human colon and patients with crohn's disease have autoantibodies to type VII collagen.Generalized pustular psoriasis and cryptogenic organizing pneumonia.Molecular cloning and characterization of a cDNA encoding canine type VII collagen non-collagenous (NC1) domain, the target antigen of autoimmune disease epidermolysis bullosa acquisita (EBA).A profile of lipid dysregulation in harlequin ichthyosis.Noonan syndrome with multiple lentigines and associated craniosynostosis.Management of cutaneous squamous cell carcinoma in patients with epidermolysis bullosa.Analysis of hedgehog signaling in periocular sebaceous carcinoma.Inherited palmoplantar keratodermas: the heart of the matter.Recessive mutation in FAM83G associated with palmoplantar keratoderma and exuberant scalp hair.
P50
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P50
description
researcher
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name
E A O'Toole
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E A O'Toole
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type
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E A O'Toole
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E A O'Toole
@nl
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E A O'Toole
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E A O'Toole
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P106
P31
P496
0000-0002-4084-4836