about
Alkylation of prohibitin by cyclohexylphenyl-chloroethyl urea on an aspartyl residue is associated with cell cycle G(1) arrest in B16 cells.Tetraspanin 8 (TSPAN 8) as a potential target for radio-immunotherapy of colorectal cancerTargeting DNA repair by coDbait enhances melanoma targeted radionuclide therapyTheranostic Approach for Metastatic Pigmented Melanoma Using ICF15002, a Multimodal Radiotracer for Both PET Imaging and Targeted Radionuclide Therapy.Tetraspanin 8 is a novel regulator of ILK-driven β1 integrin adhesion and signaling in invasive melanoma cells.MnSOD overexpression prevents liver mitochondrial DNA depletion after an alcohol binge but worsens this effect after prolonged alcohol consumption in mice.Annexin A1 in primary tumors promotes melanoma dissemination.Annexin A1 localization and its relevance to cancer.Proteoglycans as Target for an Innovative Therapeutic Approach in Chondrosarcoma: Preclinical Proof of Concept.[¹²³I]ICF01012 melanoma imaging and [¹³¹I]ICF01012 dosimetry allow adapted internal targeted radiotherapy in preclinical melanoma models.Characterization of pro-invasive mechanisms and N-terminal cleavage of ANXA1 in melanoma.Small rigid platforms functionalization with quaternary ammonium: targeting extracellular matrix of chondrosarcoma.Evaluation of two (125)I-radiolabeled acridine derivatives for Auger-electron radionuclide therapy of melanoma.Intramolecular cyclization of N-phenyl N'(2-chloroethyl)ureas leads to active N-phenyl-4,5-dihydrooxazol-2-amines alkylating β-tubulin Glu198 and prohibitin Asp40.N-(4-iodophenyl)-N'-(2-chloroethyl)urea as a microtubule disrupter: in vitro and in vivo profiling of antitumoral activity on CT-26 murine colon carcinoma cell line cultured and grafted to mice.Internal dosimetry through GATE simulations of preclinical radiotherapy using a melanin-targeting ligand.The manganese superoxide dismutase Ala16Val dimorphism modulates both mitochondrial import and mRNA stability.Antineoplastic potency of arylchloroethylurea derivatives in murine colon carcinoma.Development and characterization of a human three-dimensional chondrosarcoma culture for in vitro drug testing.A case of mitochondrial encephalomyopathy associated with a muscle coenzyme Q10 deficiency.B16 melanoma secretomes and in vitro invasiveness: syntenin as an invasion modulator.Early detection and longitudinal monitoring of experimental primary and disseminated melanoma using [¹⁰F]ICF01006, a highly promising melanoma PET tracer.(123)I-BZA2 as a melanin-targeted radiotracer for the identification of melanoma metastases: results and perspectives of a multicenter phase III clinical trial.Antibody PEGylation in bioorthogonal pretargeting with trans-cyclooctene/tetrazine cycloaddition: in vitro and in vivo evaluation in colorectal cancer models.Genetic dimorphism in superoxide dismutase and susceptibility to alcoholic cirrhosis, hepatocellular carcinoma, and death.Proteoglycan-targeting applied to hypoxia-activated prodrug therapy in chondrosarcoma: first proof-of-concept.Doxycycline and its quaternary ammonium derivative for adjuvant therapies of chondrosarcoma.A near homoplasmic T8993G mtDNA mutation in a patient with atypic Leigh syndrome not present in the mother's tissues.A large-scale RNAi screen identifies LCMR1 as a critical regulator of Tspan8-mediated melanoma invasion.In vivo efficacy of melanoma internal radionuclide therapy with a 131I-labelled melanin-targeting heteroarylcarboxamide molecule.TIP60: an actor in acetylation of H3K4 and tumor development in breast cancerTargeting the Tetraspanins with Monoclonal Antibodies in Oncology: Focus on Tspan8/Co-029Clinical, biochemical, and molecular analysis of a maternally inherited case of Leigh syndrome (MILS) associated with the mtDNA T8993G point mutationThird International Congress on Human Mitochondrial Pathology (Euromit III): towards a better understanding of energy metabolism disordersMyo-leukoencephalopathy in twins: study of 3243-myopathy, encephalopathy, lactic acidosis, and strokelike episodes mitochondrial DNA mutationMerrf family with 8344 mutation in tRNA (lys). Evidence of a mitochondrial vasculopathy in muscle biopsies[Ageing, alcohol and mitochondria]Synthesis, radiolabeling and preliminary in vivo evaluation of multimodal radiotracers for PET imaging and targeted radionuclide therapy of pigmented melanomaIntrafamilial heterogeneous clinical presentation of the mitochondrial 3243 MELAS mutation; molecular investigations among four generationsPretargeted radioimmunotherapy and SPECT imaging of peritoneal carcinomatosis using bioorthogonal click chemistry: probe selection and first proof-of-concept
P50
Q33294410-53C16C10-D1AD-461D-82CB-07D999C73D21Q33591800-AA0B0C8E-A23D-405C-A3B5-8A7CF1BC74B5Q37022343-8C843AD7-4F63-4DD4-B8B7-827DD7593992Q37505658-A37AE95B-1E5C-46F7-80EA-D5C7A93874E4Q37725588-5A0770F1-3CA8-4F35-BDDB-5AE9FFF7028AQ37869770-450965FA-E110-4167-8C89-F4329021B804Q38305975-E7FB9EA6-E8C7-4745-8B9A-0A15C1470A98Q38697447-4273590C-A39D-4C6B-99A0-7C2C5B2D8DBBQ38733976-1ECD4100-3F20-4AC0-8792-77463EEDE38DQ38924577-6819BC07-2CAF-44C5-8129-C8DD39ACEB46Q38943416-63BA7A73-DF46-4017-95F2-A3153E4C45B4Q38980403-41119777-9F02-43F8-AE60-CC7DB8F0F3CFQ39009271-A090E75D-B923-4C66-9E3D-D4107F917354Q39582193-FE3AC38C-B1A8-468A-BCA7-F9229CC29B8EQ40135845-973F8760-55F5-4F5F-ACA3-C6DC3B1D2698Q40183123-62CA2507-EEEC-4F04-ACC2-7274469516D5Q40428545-0B40845F-F4F2-4358-BE72-B600274B829BQ40528778-00265CE1-D306-4AEF-AD21-E1610246BE6BQ41007674-A179DC71-8200-4007-8DAA-EDDD07194148Q41048491-76F43D06-AED1-45F8-BE9A-996838A2E7FBQ43218059-CEE75661-7C27-4D48-803A-1D8E7BD67DC6Q43480586-94C51F22-61B7-4B97-8E5E-1732D70C4C9CQ43498641-1E6BBA4E-B5BC-4822-A3CA-13618CBAD640Q44384601-7CDE8913-4E5C-41DD-892E-2131BA2DAFE7Q46376179-7764F0CE-3991-4589-AD26-3A30ADE9E963Q47121012-05912A01-E89A-4D12-835B-CB1CBDF3A689Q48721980-8C294E7F-3FA7-4277-9202-0A4D218A824AQ48962180-691D360E-0B26-4C8A-AC22-3D9BBCB6AEC3Q51665583-AAD3E6AC-31A1-4B93-8A41-8DFD9F4AF6EBQ53120428-66216C6F-2B79-4568-8AEB-83F22CE6BE3FQ57457013-730DE24F-8657-4E94-8E74-24FAC4D1CECDQ64245581-AEA2E849-4F7B-4DD1-BCC9-8DBA08783E7EQ71376773-6960B2F8-B875-4A17-8079-D1A0A006CB37Q71479226-103CDB85-8D60-4CD5-A1B9-59A32FB1AE11Q72280476-C44DEE52-80E1-4387-B800-A2EADEAD1070Q72427717-A92FECDA-BC59-4CB5-A4A8-7C91B34F9690Q73771298-01BA8A27-949F-46CA-83C0-E912FE5D6197Q86631694-79CBF3BA-F63D-412C-883F-AB3A71386B31Q86857150-E6BFCC39-C16C-4778-8388-B8149EBD4E12Q90533514-070098E8-126A-4808-8BA7-A7FCF84ED494
P50
description
researcher
@en
wetenschapper
@nl
name
F Degoul
@en
F Degoul
@nl
type
label
F Degoul
@en
F Degoul
@nl
prefLabel
F Degoul
@en
F Degoul
@nl
P106
P31
P496
0000-0002-0206-3350