about
Mrs evaluation of brain-metabolites in extracts from cell-cultures, human tumors and normal tissue from brain - cholesteryl ester, choline containing compounds and creatine as markers for development, differentiation and pathology.Pharmacological approaches to inhibit endogenous glucose production as a means of anti-diabetic therapy.Nuclear magnetic resonance spectroscopy: biochemical evaluation of brain function in vivo and in vitro.Citrate, a Ubiquitous Key Metabolite with Regulatory Function in the CNS.Glutamate and glutamine metabolism and compartmentation in astrocytes.Utilization of glutamine and of TCA cycle constituents as precursors for transmitter glutamate and GABA.Pathologic consequences in hippocampus of aberrations in the metabolic trafficking between neurons and glial cells necessary for normal glutamate homeostasis.Neuronal-astrocytic interactions in glutamate metabolism.Peroxyvanadium compounds inhibit glucose-6-phosphatase activity and glucagon-stimulated hepatic glucose output in the rat in vivo.Characterization of glycerol uptake and glycerol kinase activity in rat hepatocytes cultured under different hormonal conditions.Citrate, beneficial or deleterious in the CNS?Metformin inhibits glycogen synthesis and gluconeogenesis in cultured rat hepatocytes.Release of alpha-ketoglutarate, malate and succinate from cultured astrocytes: possible role in amino acid neurotransmitter homeostasis.Uptake, release, and metabolism of citrate in neurons and astrocytes in primary cultures.Transport of L-[3H]arginine in cultured neurons: characteristics and inhibition by nitric oxide synthase inhibitors.A Paradigm Shift Towards Patient Involvement in Medicines Development and Regulatory ScienceMetabolic differences between primary cultures of astrocytes and neurons from cerebellum and cerebral cortex. Effects of fluorocitrateGlutamate and glutamine metabolism in cultured GABAergic neurons studied by 13C NMR spectroscopy may indicate compartmentation and mitochondrial heterogeneityMetabolism of [U-13C]glutamate in astrocytes studied by 13C NMR spectroscopy: incorporation of more label into lactate than into glutamine demonstrates the importance of the tricarboxylic acid cycleGlucose-6-phosphatase catalytic enzyme inhibitors: synthesis and in vitro evaluation of novel 4,5,6,7-tetrahydrothieno[3,2-c]- and -[2,3-c]pyridinesThe effects of isofagomine, a potent glycogen phosphorylase inhibitor, on glycogen metabolism in cultured mouse cortical astrocytesKinetic and functional characterization of 1,4-dideoxy-1, 4-imino-d-arabinitol: a potent inhibitor of glycogen phosphorylase with anti-hyperglyceamic effect in ob/ob miceN,N-dibenzyl-N'-benzylidenehydrazines: potent competitive glucose-6-phosphatase catalytic enzyme inhibitors
P50
Q33901002-3C56943C-1CDB-407B-8497-78BC7701A982Q34350560-2A81C472-EFB0-498E-9E36-3CB9AFF4E331Q36715770-6D7AC669-6881-47DB-A560-C3B63672703EQ39069512-28F41C8F-F802-4724-9FC6-07D91344BC98Q40559821-231B5677-1360-40B7-8E55-0CEE2B2C1D92Q40559826-BD9B746E-4066-4B7D-A8D6-9A556F3A03E7Q40619897-5D894EB0-2929-4E21-A5AB-9EBA90B05A95Q40708605-3F9C9FC5-117D-49AD-B05E-2921DF74FEC9Q42472345-06B024E5-C407-40F6-B977-8176C27C750EQ42542104-CE9B8C47-354E-4248-B750-6C5FC940C5C4Q43942162-D1CA0DE9-479A-42B1-886F-5084A4A1141BQ44393971-FC4BD1B0-FF1D-460F-867D-F47F9628180DQ48088151-09FB2F13-D45F-4C62-9D6D-B45BD9426FB3Q48136106-5D952455-3D82-4477-B3B6-49986C84CD69Q48264468-CDB4A1B8-BAC4-40BC-A459-4D956FAF2AB8Q60325471-B38399FB-E2E9-439C-BC0A-98300A4AD8F1Q72000469-32135864-A605-4AD3-8CEC-04DC2CE73B83Q72194019-5BA71B5A-E5D9-4CF0-BED9-E20CB6F2DC0FQ72230148-2B4528DE-F07C-4052-9C43-7F4C689342FEQ73064880-2AAD900F-B141-40BC-A292-676E154CAE76Q73583772-D2F0DD1A-CB55-4FB5-AF69-EF9C502F7B0AQ74138696-FDA223EC-ED9C-421B-AEC3-3AB9871C11CEQ74403386-079B0C7C-F8A4-4967-A9DD-C2CE7B29FBAC
P50
description
researcher
@en
wetenschapper
@nl
name
N Westergaard
@en
N Westergaard
@nl
type
label
N Westergaard
@en
N Westergaard
@nl
prefLabel
N Westergaard
@en
N Westergaard
@nl
P106
P31
P496
0000-0002-2663-8040