about
sameAs
Ability of HIV-1 Nef to downregulate CD4 and HLA class I differs among viral subtypesSelection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infectionOngoing burden of disease and mortality from HIV/CMV coinfection in Africa in the antiretroviral therapy eraIVA: accurate de novo assembly of RNA virus genomesStatistical resolution of ambiguous HLA typing dataBroad and Gag-biased HIV-1 epitope repertoires are associated with lower viral loads.Phylogenetic dependency networks: inferring patterns of CTL escape and codon covariation in HIV-1 Gag.Immunodominant HIV-1 Cd4+ T cell epitopes in chronic untreated clade C HIV-1 infection.Replicative capacity of human immunodeficiency virus type 1 transmitted from mother to child is associated with pediatric disease progression rateHIV subtype influences HLA-B*07:02-associated HIV disease outcome.Amino-acid co-variation in HIV-1 Gag subtype C: HLA-mediated selection pressure and compensatory dynamics.The majority of currently circulating human immunodeficiency virus type 1 clade B viruses fail to prime cytotoxic T-lymphocyte responses against an otherwise immunodominant HLA-A2-restricted epitope: implications for vaccine design.HLA-B63 presents HLA-B57/B58-restricted cytotoxic T-lymphocyte epitopes and is associated with low human immunodeficiency virus loadLong-term control of HIV-1 in hemophiliacs carrying slow-progressing allele HLA-B*5101Additive contribution of HLA class I alleles in the immune control of HIV-1 infection.Gag-protease-mediated replication capacity in HIV-1 subtype C chronic infection: associations with HLA type and clinical parametersImmunodominant HIV-1-specific HLA-B- and HLA-C-restricted CD8+ T cells do not differ in polyfunctionality.Programmed death-1 expression on HIV-1-specific CD8+ T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load.Impact of HLA selection pressure on HIV fitness at a population level in Mexico and Barbados.Consistent patterns in the development and immunodominance of human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T-cell responses following acute HIV-1 infectionCo-operative additive effects between HLA alleles in control of HIV-1Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1Adaptation of HIV-1 to human leukocyte antigen class INef-mediated down-regulation of CD4 and HLA class I in HIV-1 subtype C infection: association with disease progression and influence of immune pressure.CD8+ T Cell Breadth and Ex Vivo Virus Inhibition Capacity Distinguish between Viremic Controllers with and without Protective HLA Class I Alleles.Impact of HLA-driven HIV adaptation on virulence in populations of high HIV seroprevalence.Progression to AIDS in South Africa is associated with both reverting and compensatory viral mutations.Impairment of CD1d-restricted natural killer T cells in chronic HIV type 1 clade C infection.Nef-specific CD8+ T cell responses contribute to HIV-1 immune control.A randomised, placebo-controlled, first-in-human study of a novel clade C therapeutic peptide vaccine administered ex vivo to autologous white blood cells in HIV infected individuals.Influence of Gag-protease-mediated replication capacity on disease progression in individuals recently infected with HIV-1 subtype C.Enhanced detection of human immunodeficiency virus type 1-specific T-cell responses to highly variable regions by using peptides based on autologous virus sequences.Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-amino-acid difference between HLA class I subtypesDiscordant Impact of HLA on Viral Replicative Capacity and Disease Progression in Pediatric and Adult HIV Infection.HLA-B*57 Micropolymorphism shapes HLA allele-specific epitope immunogenicity, selection pressure, and HIV immune controlLack of association between HLA class II alleles and in vitro replication capacities of recombinant viruses encoding HIV-1 subtype C Gag-protease from chronically infected individuals.Sex Differences in Antiretroviral Therapy Initiation in Pediatric HIV Infection.Disease progression despite protective HLA expression in an HIV-infected transmission pairExtensive intrasubtype recombination in South African human immunodeficiency virus type 1 subtype C infections.Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infection.
P50
Q21245213-67BEBC69-A892-44A5-94EC-40F076D28523Q24564623-3CE7C0F4-24C6-464A-B4E1-E345351C53ACQ26781359-E0F820CD-1119-4581-B6A1-54299C4197CCQ28647368-88A59B86-55D3-4ED0-8B36-CEACE95F2BEEQ31151639-FBE77454-E0EE-4B4F-8AB8-52164839BC60Q33313878-239A61D5-FFEC-4E10-A070-7102AD8F4CA7Q33385995-F739CA7A-E8BD-4825-A9CC-C2803EC5C381Q33427803-9528AB67-BA54-4426-80E0-736C9FED4DB5Q33558599-683A9333-B423-4754-A93B-D3E2DF881A98Q33566546-5006C6B0-F770-4135-9CE4-1A84A2E25066Q33687232-CC0B7250-19C7-4AFF-8CEE-5AE3513C844BQ33724305-2270B39B-6389-4A7E-A397-6D2E92219D5EQ33911914-3501BE09-D1CF-47E5-8725-6369B586A6CBQ33966626-EBC74B54-9903-4916-A519-855855563990Q34120809-B7C826B1-4093-4276-9BAE-0AE5521B9E76Q34178349-543C95BE-195E-40E8-B757-972E7E26F364Q34195857-D89A6041-8D0F-4E71-918E-C5C577D4B6CFQ34197037-7E70DABB-FC8A-477A-9C4C-7D7B1354CB4DQ34262204-98F8E797-FE28-4B42-9EAF-C2E6F439CA17Q34361731-8A82AA3F-E8FC-4C7F-95AC-C45B91280D51Q34456570-003E2F90-072F-43A3-9F68-1D02C7757AF6Q34545760-328D1176-0EAC-41AD-8370-A24D73D479E4Q34604811-7A145630-4CD7-4EFA-951D-1D60CCF71FE9Q34613552-1805E876-5AB8-48D7-BA13-DBCE281056DBQ34677320-0E465D1F-D1F4-416E-AEB3-1875C7A6F382Q34753286-3BDDAEA1-FE1B-4126-A96A-3AB0755DE851Q34841789-E385DA5A-2CC4-4399-8267-B672D05A39E0Q34875335-BD2632AE-3715-416B-98BD-DE9C9246BD4DQ34984237-4E224D85-4C63-4028-A262-BE9E377D795EQ34998830-5676C9BB-BC50-4A26-97A1-D9C95BF3EE18Q35076519-7B8663EC-CDB7-4C92-A41D-473E3571233FQ35149407-48B5DBA9-3001-44BF-836E-46423C6B2A4AQ35635344-0678ED23-9C5D-4776-8A13-36DA62F683A0Q35664125-86F0FEBC-04B2-4A34-ADCF-BDFB5A62C04FQ35665876-64986CD9-CD8A-4ED2-95A5-28AE791E4E73Q35665911-5497F66C-B024-4816-BE19-2ADF7B065484Q35685183-75F6F889-A9B0-4272-9DD7-03A37730B0DAQ35804078-92EA6538-ABA1-4CE5-B39C-8BAF930765E1Q35857346-69490478-C236-4542-82DE-797C9C682DECQ35947590-5DBC3E3F-863C-4E10-8AA9-58E59325D679
P50
description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Philip Goulder
@nl
Philip J. R. Goulder
@en
type
label
Philip Goulder
@nl
Philip J. R. Goulder
@en
altLabel
Goulder P
@en
Goulder P. J. R.
@en
Goulder P.
@en
Goulder PJR
@en
Goulder
@en
P Goulder
@en
P J R Goulder
@en
P. Goulder
@en
P. J. R. Goulder
@en
PJR Goulder
@en
prefLabel
Philip Goulder
@nl
Philip J. R. Goulder
@en
P21
P31
P496
0000-0002-9842-4674