about
Localization and comparative analysis of acid-sensing ion channel (ASIC1, 2, and 3) mRNA expression in mouse colonic sensory neurons within thoracolumbar dorsal root ganglia.Acid sensing ion channels 2 and 3 are required for inhibition of visceral nociceptors by benzamil.A novel role for TRPM8 in visceral afferent function.Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects.Multiple roles for NaV1.9 in the activation of visceral afferents by noxious inflammatory, mechanical, and human disease-derived stimuli.The pharmacology of gastrointestinal nociceptive pathways.GABA(B) receptor-mediated effects on vagal pathways to the lower oesophageal sphincter and heartVagal neurotransmission to the ferret lower oesophageal sphincter: inhibition via GABA(B) receptors.Neuroanatomy of extrinsic afferents supplying the gastrointestinal tract.Different in vitro and in vivo profiles of substituted 3-aminopropylphosphinate and 3-aminopropyl(methyl)phosphinate GABA(B) receptor agonists as inhibitors of transient lower oesophageal sphincter relaxation.Selective role for TRPV4 ion channels in visceral sensory pathways.Identification of medium/high-threshold extrinsic mechanosensitive afferent nerves to the gastrointestinal tract.Emerging receptor target in the pharmacotherapy of irritable bowel syndrome with constipation.Transient receptor potential cation channels in visceral sensory pathways.Distinct afferent innervation patterns within the human proximal and distal esophageal mucosa.Vagal mechanoreceptors and chemoreceptors in mouse stomach and esophagus.Cannabinoid receptor agonism inhibits transient lower esophageal sphincter relaxations and reflux in dogs.Excitation of rat colonic afferent fibres by 5-HT(3) receptors.Gastric vagal afferent modulation by leptin is influenced by food intake status.TRPA1 contributes to specific mechanically activated currents and sensory neuron mechanical hypersensitivity.Metabotropic glutamate receptors inhibit mechanosensitivity in vagal sensory neurons.Nitric oxide as an endogenous peripheral modulator of visceral sensory neuronal function.Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia.Expression of taste molecules in the upper gastrointestinal tract in humans with and without type 2 diabetes.Differential chemosensory function and receptor expression of splanchnic and pelvic colonic afferents in mice.Transient lower esophageal sphincter relaxations in dogs are inhibited by a metabotropic glutamate receptor 5 antagonist.Anatomy and function of group III metabotropic glutamate receptors in gastric vagal pathways.Inhibition of mechanosensitivity in visceral primary afferents by GABAB receptors involves calcium and potassium channels.Involvement of metabotropic glutamate 5 receptor in visceral pain.Modulation of murine gastric vagal afferent mechanosensitivity by neuropeptide W.The ion channel ASIC1 contributes to visceral but not cutaneous mechanoreceptor function.Role of TRPV1 in high-threshold rat colonic splanchnic afferents is revealed by inflammation.Visceral pain readouts in experimental medicine.Peripheral versus central modulation of gastric vagal pathways by metabotropic glutamate receptor 5.Sensory and motor innervation of the crural diaphragm by the vagus nerves.A chronic high fat diet alters the homologous and heterologous control of appetite regulating peptide receptor expression.Ghrelin selectively reduces mechanosensitivity of upper gastrointestinal vagal afferents.Sprouting of colonic afferent central terminals and increased spinal mitogen-activated protein kinase expression in a mouse model of chronic visceral hypersensitivityThe Hot Mustard Receptor's Role in Gut Motor FunctionPharmacologic treatments for esophageal disorders
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description
researcher
@en
wetenschapper
@nl
name
L A Blackshaw
@en
L A Blackshaw
@nl
type
label
L A Blackshaw
@en
L A Blackshaw
@nl
prefLabel
L A Blackshaw
@en
L A Blackshaw
@nl
P106
P31
P496
0000-0003-1565-0850