about
Whole-genome experimental identification of insertion/deletion polymorphisms of interspersed repeats by a new general approachA technique for genome-wide identification of differences in the interspersed repeats integrations between closely related genomes and its application to detection of human-specific integrations of HERV-K LTRs.tcR: an R package for T cell receptor repertoire advanced data analysis.Individual characterization of stably expanded T cell clones in ankylosing spondylitis patients.[The oligoclonal expansion of T cells: study of its stability over time]Normalization of genomic DNA using duplex-specific nuclease.Quantitative tracking of T cell clones after haematopoietic stem cell transplantation.Persisting fetal clonotypes influence the structure and overlap of adult human T cell receptor repertoiresA new set of markers for human identification based on 32 polymorphic Alu insertions.Next generation sequencing for TCR repertoire profiling: platform-specific features and correction algorithms.Endogenous retroviruses and human evolutionPreparing unbiased T-cell receptor and antibody cDNA libraries for the deep next generation sequencing profiling.The evidence for increased L1 activity in the site of human adult brain neurogenesis.Distinctive properties of identical twins' TCR repertoires revealed by high-throughput sequencing.Genome-wide experimental identification and functional analysis of human specific retroelements.Large-scale determination of the methylation status of retrotransposons in different tissues using a methylation tags approach.Mother and child T cell receptor repertoires: deep profiling study.Quantitative profiling of immune repertoires for minor lymphocyte counts using unique molecular identifiers.Age-related decrease in TCR repertoire diversity measured with deep and normalized sequence profiling.Contribution of functional KIR3DL1 to ankylosing spondylitis.Positioning of 72 potentially full size LTRs of human endogenous retroviruses HERV-K on the human chromosome 19 map. Occurrences of the LTRs in human gene sites.Unusually long target site duplications flanking some of the long terminal repeats of human endogenous retrovirus K in the human genome.Human trash ESTs--sequences from cDNA collection that are not aligned to genome assembly.From East to West: patterns of genetic diversity of populations living in four Eurasian regions.A human endogenous retrovirus-like (HERV) LTR formed more than 10 million years ago due to an insertion of HERV-H LTR into the 5' LTR of HERV-K is situated on human chromosomes 10, 19 and Y.Subfamilies and nearest-neighbour dendrogram for the LTRs of human endogenous retroviruses HERV-K mapped on human chromosome 19: physical neighbourhood does not correlate with identity level.[Human genome-specific HERV-K intron LTR genes have a random orientation relative to the direction of transcription, and, possibly, participated in antisense gene expression regulation]Human-specific subfamilies of HERV-K (HML-2) long terminal repeats: three master genes were active simultaneously during branching of hominoid lineages.Tracking T-cell immune reconstitution after TCRαβ/CD19-depleted hematopoietic cells transplantation in children.Quantitative profiling reveals minor changes of T cell receptor repertoire in response to subunit inactivated influenza vaccine.Reliability of immune receptor rearrangements as genetic markers for minimal residual disease monitoring.CD8+ T cells with characteristic T cell receptor beta motif are detected in blood and expanded in synovial fluid of ankylosing spondylitis patients.[A novel approach to identification of somatic retroelements' insertions in human genome].Method for identification of condition-associated public antigen receptor sequences.First autologous hematopoietic SCT for ankylosing spondylitis: a case report and clues to understanding the therapyAn advanced enrichment method for rare somatic retroelement insertions sequencingPrecise tracking of vaccine-responding T cell clones reveals convergent and personalized response in identical twinsSolitary HERV-K LTRs possess bi-directional promoter activity and contain a negative regulatory element in the U5 regionLong terminal repeats of human endogenous retrovirus K family (HERV-K) specifically bind host cell nuclear proteinsFull-sized HERV-K (HML-2) human endogenous retroviral LTR sequences on human chromosome 21: map locations and evolutionary history
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P50
description
researcher
@en
wetenschapper
@nl
name
Juri Borissowitsch Lebedew
@de
Yuri Lebedev
@en
Yuri Lebedev
@nl
Юрий Борисович Лебедев
@ru
type
label
Juri Borissowitsch Lebedew
@de
Yuri Lebedev
@en
Yuri Lebedev
@nl
Юрий Борисович Лебедев
@ru
altLabel
Juri Lebedew
@de
Yury Borisovich Lebedev
@en
Yury Lebedev
@en
prefLabel
Juri Borissowitsch Lebedew
@de
Yuri Lebedev
@en
Yuri Lebedev
@nl
Юрий Борисович Лебедев
@ru
P106
P21
P31
P496
0000-0003-4554-4733