about
Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotypeThe CD46-Jagged1 interaction is critical for human TH1 immunityExperimentally-induced anti-myeloperoxidase vasculitis does not require properdin, MASP-2 or bone marrow-derived C5Membrane cofactor protein (MCP; CD46) expression in transgenic miceCD46-induced immunomodulatory CD4+ T cells express the adhesion molecule and chemokine receptor pattern of intestinal T cellsComplement Regulates Nutrient Influx and Metabolic Reprogramming during Th1 Cell ResponsesCD46 engagement on human CD4+ T cells produces T regulatory type 1-like regulation of antimycobacterial T cell responsesT-cell stimulation and regulation: with complements from CD46.CD46 Activation Regulates miR-150-Mediated Control of GLUT1 Expression and Cytokine Secretion in Human CD4+ T Cells.The complement protein properdin binds apoptotic T cells and promotes complement activation and phagocytosis.Cloning and recombinant expression of a barred sand bass (Paralabrax nebulifer) cDNA. The encoded protein displays structural homology and immunological crossreactivity to human complement/cofactor related plasma proteins.Properdin: New roles in pattern recognition and target clearance.T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells.Complement-Mediated Regulation of Metabolism and Basic Cellular ProcessesIntracellular complement activation sustains T cell homeostasis and mediates effector differentiation.Keeping It All Going-Complement Meets MetabolismAnti-myeloperoxidase antibodies attenuate the monocyte response to LPS and shape macrophage development.Graft dysfunction in chronic antibody-mediated rejection correlates with B-cell-dependent indirect antidonor alloresponses and autocrine regulation of interferon-γ production by Th1 cells.Complement: coming full circle.Properdin: emerging roles of a pattern-recognition molecule.CD46 in innate and adaptive immunity: an update.Novel roles for complement receptors in T cell regulation and beyond.CD46: the 'multitasker' of complement proteins.Complement nomenclature 2014.Dysregulated CD46 shedding interferes with Th1-contraction in systemic lupus erythematosus.The "ins and outs" of complement-driven immune responses.Intracellular complement - the complosome - in immune cell regulation.A TSLP-complement axis mediates neutrophil killing of methicillin-resistant Staphylococcus aureus.Immune dysregulation in Alagille syndrome: A new feature of the evolving phenotype.Complement-induced regulatory T cells suppress T-cell responses but allow for dendritic-cell maturation.Human complement C3 deficiency: Th1 induction requires T cell-derived complement C3a and CD46 activation.Induction of a regulatory phenotype in human CD4+ T cells by streptococcal M protein.The competitive nature of signal transducer and activator of transcription complex formation drives phenotype switching of T cells.Enzymatic Reactions and Detection of C3 Cleavage Fragments.Ancient origin of human complement factor H.C3a modulates IL-1β secretion in human monocytes by regulating ATP efflux and subsequent NLRP3 inflammasome activation.Human plasma C3 is essential for the development of memory B, but not T, lymphocytes.Targeting the Dark Horse of complement: the first generation of functionally selective C5aR2 ligands.Complement and the Regulation of T Cell Responses.The intestinal complement system in inflammatory bowel disease: Shaping intestinal barrier function.
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description
researcher
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wetenschapper
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C Kemper
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C Kemper
@nl
type
label
C Kemper
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C Kemper
@nl
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C Kemper
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C Kemper
@nl
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0000-0003-4196-1417