about
USP14 inhibits ER-associated degradation via interaction with IRE1alphaMammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.Stress responses from the endoplasmic reticulum in cancerApoptosis signal-regulating kinase 1 (ASK1) induces neuronal differentiation and survival of PC12 cellsASK1 inhibits interleukin-1-induced NF-kappa B activity through disruption of TRAF6-TAK1 interactionPre-emptive Quality Control Protects the ER from Protein Overload via the Proximity of ERAD Components and SRPActivation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis factor receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin.Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice.Roles of MAPKKK ASK1 in stress-induced cell death.RbAp48 is essential for viability of vertebrate cells and plays a role in chromosome stability.Survival and apoptosis signals in ER stress: the role of protein kinases.ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis.Targeting ASK1 in ER stress-related neurodegenerative diseases.The expression of Fn14 via mechanical stress-activated JNK contributes to apoptosis induction in osteoblasts.Signaling pathways from the endoplasmic reticulum and their roles in diseaseIdentification of a novel bone morphogenetic protein-responsive gene that may function as a noncoding RNA.Histone acetyltransferase PCAF is involved in transactivation of Bcl-6 and Pax5 genes in immature B cells.Paired box gene 5 isoforms A and B have different functions in transcriptional regulation of B cell development-related genes in immature B cells.Lack of GCN5 remarkably enhances the resistance against prolonged endoplasmic reticulum stress-induced apoptosis through up-regulation of Bcl-2 gene expression.Histone acetyltransferase p300/CBP-associated factor is an effective suppressor of secretory immunoglobulin synthesis in immature B cells.ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1.GCN5 is involved in regulation of immunoglobulin heavy chain gene expression in immature B cells.GCN5 protects vertebrate cells against UV-irradiation via controlling gene expression of DNA polymerase η.ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity.A systematic immunoprecipitation approach reinforces the concept of common conformational alterations in amyotrophic lateral sclerosis-linked SOD1 mutants.SOD1 as a molecular switch for initiating the homeostatic ER stress response under zinc deficiency.Tumor growth inhibition by arsenic trioxide (As2O3) in the orthotopic metastasis model of androgen-independent prostate cancer.The cytoplasmic domain of Alzheimer's amyloid-beta protein precursor causes sustained apoptosis signal-regulating kinase 1/c-Jun NH2-terminal kinase-mediated neurotoxic signal via dimerization.The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.Role of the unfolded protein response in the development of central nervous system.A mouse model reveals that Mfsd2a is critical for unfolded protein response upon exposure to tunicamycin.The ASK1-specific inhibitors K811 and K812 prolong survival in a mouse model of amyotrophic lateral sclerosis.[Molecular mechanisms of ALS-linked mutant SOD1-induced motor neuron death].Molecular mechanism of ER stress-induced pre-emptive quality control involving association of the translocon, Derlin-1, and HRD1.A novel monoclonal antibody reveals a conformational alteration shared by amyotrophic lateral sclerosis-linked SOD1 mutantsASK3 responds to osmotic stress and regulates blood pressure by suppressing WNK1-SPAK/OSR1 signaling in the kidneyGrowth/Differentiation Factor-5 Induces Angiogenesisin Vivo[Identification of receptors for bone morphogenetic proteins]CHOP is a multifunctional transcription factor in the ER stress responseGCN5 is essential for IRF-4 gene expression followed by transcriptional activation of Blimp-1 in immature B cells
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P50
description
researcher
@en
wetenschapper
@nl
name
Hideki Nishitoh
@en
Hideki Nishitoh
@nl
type
label
Hideki Nishitoh
@en
Hideki Nishitoh
@nl
prefLabel
Hideki Nishitoh
@en
Hideki Nishitoh
@nl
P106
P31
P496
0000-0002-8652-4109