about
Importance of conserved Thr214 in domain A of the Na+,K+ -ATPase for stabilization of the phosphoryl transition state complex in E2P dephosphorylationNeurological disease mutations of α3 Na+,K+-ATPase: Structural and functional perspectives and rescue of compromised function.The C terminus of Na+,K+-ATPase controls Na+ affinity on both sides of the membrane through Arg935.Importance of a Potential Protein Kinase A Phosphorylation Site of Na+,K+-ATPase and Its Interaction Network for Na+ BindingRelationship between intracellular Na+ concentration and reduced Na+ affinity in Na+,K+-ATPase mutants causing neurological disease.Mutational effects on conformational changes of the dephospho- and phospho-forms of the Na+,K+-ATPase.Interaction between the catalytic site and the A-M3 linker stabilizes E2/E2P conformational states of Na+,K+-ATPase.Identification and function of a cytoplasmic K+ site of the Na+, K+ -ATPase.Mutations Phe785Leu and Thr618Met in Na+,K+-ATPase, associated with familial rapid-onset dystonia parkinsonism, interfere with Na+ interaction by distinct mechanisms.Functional consequences of the CAPOS mutation E818K of Na,K-ATPaseImportance of transmembrane segment M3 of Na+,K+-ATPase for control of conformational changes and the cytoplasmic entry pathway for Na
P50
Q28569253-B3E92086-9693-4E9E-9F90-501C73352098Q30392400-90F8C42D-D8C3-4DD5-889E-6624CCF36A25Q37253968-F7942A25-D38F-45A3-8760-12C4E73CC5FCQ41511630-D9C0CF87-284A-4021-B15C-97EBDCEC7545Q41816343-04A237AD-06E4-414E-B125-FD6B9E021379Q43593848-E41E4011-BFED-4329-9F64-D47EFCACA0D1Q45169963-C2898AC8-9262-4A92-9BE8-3C0E434558BFQ46453371-FDB264B5-168F-43DA-9F87-5E2AC6D943A5Q48571523-457AE4DD-B447-4A8A-BAA2-D30201E557A6Q58582465-FB19FCA3-6ADD-497C-97F4-48C02B6DAEFFQ73430378-82FB1FB0-E811-44DE-9518-F157DFDCFF50
P50
description
researcher
@en
wetenschapper
@nl
name
Mads Toustrup-Jensen
@en
Mads Toustrup-Jensen
@nl
type
label
Mads Toustrup-Jensen
@en
Mads Toustrup-Jensen
@nl
prefLabel
Mads Toustrup-Jensen
@en
Mads Toustrup-Jensen
@nl
P106
P31
P496
0000-0003-2064-5861