about
Angiotensin II differentially regulates interleukin-1-beta-inducible NO synthase (iNOS) and vascular cell adhesion molecule-1 (VCAM-1) expression: role of p38 MAPKGlucose-6 phosphate dehydrogenase deficiency decreases the vascular response to angiotensin IIAMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant miceS-glutathiolation of Ras mediates redox-sensitive signaling by angiotensin II in vascular smooth muscle cells.Atlas-derived perfusion correlates of white matter hyperintensities in patients with reduced cardiac outputAttenuated cardiovascular hypertrophy and oxidant generation in response to angiotensin II infusion in glutaredoxin-1 knockout mice.Redox regulation of sirtuin-1 by S-glutathiolation.Nitroxyl activates SERCA in cardiac myocytes via glutathiolation of cysteine 674.Detailed map of oxidative post-translational modifications of human p21ras using Fourier transform mass spectrometry.IκBβ attenuates angiotensin II-induced cardiovascular inflammation and fibrosis in mice.High-fat diet increases and the polyphenol, S17834, decreases acetylation of the sirtuin-1-dependent lysine-382 on p53 and apoptotic signaling in atherosclerotic lesion-prone aortic endothelium of normal miceRegulation of cell physiology and pathology by protein S-glutathionylation: lessons learned from the cardiovascular system.Quantification of oxidative posttranslational modifications of cysteine thiols of p21ras associated with redox modulation of activity using isotope-coded affinity tags and mass spectrometry.ATVB in focus: Diabetic vascular disease: pathophysiological mechanisms in the diabetic milieu and therapeutic implications.Peroxynitrite and vascular endothelial dysfunction in diabetes mellitus.The polyphenols resveratrol and S17834 prevent the structural and functional sequelae of diet-induced metabolic heart disease in mice.Thiol oxidation in signaling and response to stress: detection and quantification of physiological and pathophysiological thiol modifications.Role of nitric oxide in diabetic complications.Nitric-oxide-induced vasodilatation: regulation by physiologic s-glutathiolation and pathologic oxidation of the sarcoplasmic endoplasmic reticulum calcium ATPase.Endomembrane H-Ras controls vascular endothelial growth factor-induced nitric-oxide synthase-mediated endothelial cell migrationLower cardiac output is associated with greater white matter hyperintensities in older adults with cardiovascular disease.Systemic hypoperfusion is associated with executive dysfunction in geriatric cardiac patients.Targeting the redox regulation of SERCA in vascular physiology and disease.Executive impairments predict functional declines in vascular dementia.Upregulation of Nox4 by TGF{beta}1 oxidizes SERCA and inhibits NO in arterial smooth muscle of the prediabetic Zucker rat.Modulation by peroxynitrite of Akt- and AMP-activated kinase-dependent Ser1179 phosphorylation of endothelial nitric oxide synthase.Role of superoxide anion in regulating pressor and vascular hypertrophic response to angiotensin II.Antioxidant improves smooth muscle sarco/endoplasmic reticulum Ca(2+)-ATPase function and lowers tyrosine nitration in hypercholesterolemia and improves nitric oxide-induced relaxation.Quantitative assessment of tyrosine nitration of manganese superoxide dismutase in angiotensin II-infused rat kidney.Activation of 5'-AMP-activated kinase is mediated through c-Src and phosphoinositide 3-kinase activity during hypoxia-reoxygenation of bovine aortic endothelial cells. Role of peroxynitrite.Temporal control of NF-kappaB activation by ERK differentially regulates interleukin-1beta-induced gene expression.Detection of sequence-specific tyrosine nitration of manganese SOD and SERCA in cardiovascular disease and aging.Activation of thromboxane receptor upregulates interleukin (IL)-1beta-induced VCAM-1 expression through JNK signaling.Activation of protein kinase C zeta by peroxynitrite regulates LKB1-dependent AMP-activated protein kinase in cultured endothelial cells.Cysteine-674 of the sarco/endoplasmic reticulum calcium ATPase is required for the inhibition of cell migration by nitric oxideS-glutathiolation of p21ras by peroxynitrite mediates endothelial insulin resistance caused by oxidized low-density lipoproteinGrowth factors enhance interleukin-1 beta-induced persistent activation of nuclear factor-kappa B in rat vascular smooth muscle cellsPreconditioning enters the era of "physiological proteomics"Acetaminophen inhibits prostanoid synthesis by scavenging the PGHS-activator peroxynitriteThe endothelium-derived hyperpolarizing factor puzzle: a mechanism without a mediator?
P50
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P50
description
researcher
@en
wetenschapper
@nl
name
Richard A Cohen
@en
Richard A Cohen
@nl
type
label
Richard A Cohen
@en
Richard A Cohen
@nl
prefLabel
Richard A Cohen
@en
Richard A Cohen
@nl
P106
P31
P496
0000-0002-1070-6408