about
Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin bindingThe ORC1 cycle in human cells: II. Dynamic changes in the human ORC complex during the cell cycle.The ORC1 cycle in human cells: I. cell cycle-regulated oscillation of human ORC1.BMCC1, which is an interacting partner of BCL2, attenuates AKT activity, accompanied by apoptosis.Transcriptional regulation of BMCC1 mediated by E2F1 in neuroblastoma cells.Novel adaptor protein Shf interacts with ALK receptor and negatively regulates its downstream signals in neuroblastoma.Involvement of human ORC and TRF2 in pre-replication complex assembly at telomeres.Deregulation of Cdt1 induces chromosomal damage without rereplication and leads to chromosomal instability.Redundant and differential regulation of multiple licensing factors ensures prevention of re-replication in normal human cells.Programmed expression of pro-apoptotic BMCC1 during apoptosis, triggered by DNA damage in neuroblastoma cells.
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description
researcher
@en
wetenschapper
@nl
name
Yasutoshi Tatsumi
@en
Yasutoshi Tatsumi
@nl
type
label
Yasutoshi Tatsumi
@en
Yasutoshi Tatsumi
@nl
prefLabel
Yasutoshi Tatsumi
@en
Yasutoshi Tatsumi
@nl
P106
P31
P496
0000-0003-2646-7410