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Molecular basis for beta-glucosidase inhibition by ring-modified calystegine analogues6-Amino-6-deoxy-5,6-di-N-(N'-octyliminomethylidene)nojirimycin: synthesis, biological evaluation, and crystal structure in complex with acid beta-glucosidaseGlycosidase inhibition by ring-modified castanospermine analogues: tackling enzyme selectivity by inhibitor tailoringCastanospermine-trehazolin hybrids: a new family of glycomimetics with tuneable glycosidase inhibitory properties.Synthesis and biological evaluation of guanidine-type iminosugars.Inhibitor versus chaperone behaviour of d-fagomine, DAB and LAB sp(2)-iminosugar conjugates against glycosidases: A structure-activity relationship study in Gaucher fibroblasts.Bicyclic derivatives of L-idonojirimycin as pharmacological chaperones for neuronopathic forms of Gaucher disease.Potent Glycosidase Inhibition with Heterovalent Fullerenes: Unveiling the Binding Modes Triggering Multivalent Inhibition.A bicyclic 1-deoxygalactonojirimycin derivative as a novel pharmacological chaperone for GM1 gangliosidosis.Fluorescent-tagged sp2-iminosugars with potent β-glucosidase inhibitory activity.One-step synthesis of non-anomeric sugar isothiocyanates from sugar azides.Topological effects and binding modes operating with multivalent iminosugar-based glycoclusters and mannosidases.o-Xylylene protecting group in carbohydrate chemistry: application to the regioselective protection of a single vic-diol segment in cyclodextrins.Synthesis of thiohydantoin-castanospermine glycomimetics as glycosidase inhibitors.Multivalent iminosugars to modulate affinity and selectivity for glycosidases.The Impact of Heteromultivalency in Lectin Recognition and Glycosidase Inhibition: An Integrated Mechanistic Study.Fluorinated Chaperone-β-Cyclodextrin Formulations for β-Glucocerebrosidase Activity Enhancement in Neuronopathic Gaucher Disease.Giant Glycosidase Inhibitors: First- and Second-Generation Fullerodendrimers with a Dense Iminosugar Shell.Synthesis of β-galactosylamides as ligands of the peanut lectin. Insights into the recognition process.Targeted delivery of pharmacological chaperones for Gaucher disease to macrophages by a mannosylated cyclodextrin carrier.Tuning glycosidase inhibition through aglycone interactions: pharmacological chaperones for Fabry disease and GM1 gangliosidosisAmphiphilic 1-Deoxynojirimycin Derivatives through Click Strategies for Chemical Chaperoning in N370S Gaucher CellsGeneralized Anomeric Effect ingem-Diamines: Stereoselective Synthesis of α-N-Linked Disaccharide MimicsIntramolecular Benzyl Protection Delivery: A Practical Synthesis of DMDP and DGDP fromd-FructoseRigid Spacer-Mediated Synthesis of Bis-Spiroketal Ring Systems: Stereoselective Synthesis of Nonsymmetrical Spiro DisaccharidesGeneralized Anomeric Effect in Action: Synthesis and Evaluation of Stable Reducing Indolizidine Glycomimetics as Glycosidase Inhibitors
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description
researcher
@en
name
M I García Moreno
@en
M I García Moreno
@nl
type
label
M I García Moreno
@en
M I García Moreno
@nl
prefLabel
M I García Moreno
@en
M I García Moreno
@nl
P106
P31
P496
0000-0003-4273-3010