about
Identification of human proteins that modify misfolding and proteotoxicity of pathogenic ataxin-1Preferred analysis methods for Affymetrix GeneChips revealed by a wholly defined control datasetRequirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signalingTransmembrane protein 198 promotes LRP6 phosphorylation and Wnt signaling activationSecretion of Wnt ligands requires Evi, a conserved transmembrane proteinAn integrated gene annotation and transcriptional profiling approach towards the full gene content of the Drosophila genomeFlyRNAi: the Drosophila RNAi screening center database.Functional analysis of the Drosophila embryonic germ cell transcriptome by RNA interferenceRefining Pathways: A Model Comparison ApproachEndothelial RSPO3 Controls Vascular Stability and Pruning through Non-canonical WNT/Ca(2+)/NFAT SignalingKeap1-Independent Regulation of Nrf2 Activity by Protein Acetylation and a BET Bromodomain ProteinGenome-wide RNAi as a route to gene function in Drosophila.An RNA interference screen identifies Inhibitor of Apoptosis Protein 2 as a regulator of innate immune signalling in Drosophila.Cellular phenotyping by RNAi.High-throughput RNAi screening to dissect cellular pathways: a how-to guide.web cellHTS2: a web-application for the analysis of high-throughput screening data.A combined ex vivo and in vivo RNAi screen for notch regulators in Drosophila reveals an extensive notch interaction network.GenomeRNAi: a database for cell-based RNAi phenotypes. 2009 update.Design and evaluation of genome-wide libraries for RNA interference screensThe lncRNA VELUCT strongly regulates viability of lung cancer cells despite its extremely low abundance.The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cellsMolecular dissection of Wnt3a-Frizzled8 interaction reveals essential and modulatory determinants of Wnt signaling activity.Extracting quantitative genetic interaction phenotypes from matrix combinatorial RNAi.Identification of JAK/STAT signalling components by genome-wide RNA interference.A novel inflammatory pathway mediating rapid hepcidin-independent hypoferremia.A map of directional genetic interactions in a metazoan cell.The promise and perils of Wnt signaling through beta-catenin.A novel phenotypic dissimilarity method for image-based high-throughput screens.A high-throughput RNAi screen for detection of immune-checkpoint molecules that mediate tumor resistance to cytotoxic T lymphocytesDpp/Gbb signaling is required for normal intestinal regeneration during infection.Amplicon sequencing of colorectal cancer: variant calling in frozen and formalin-fixed samples.Managing the genome: microRNAs in Drosophila.caRpools: an R package for exploratory data analysis and documentation of pooled CRISPR/Cas9 screens.A genetic interaction map of cell cycle regulators.CRISPR library designer (CLD): software for multispecies design of single guide RNA librariesA Protocol for a High-Throughput Multiplex Cell Viability Assay.HTSvis: a web app for exploratory data analysis and visualization of arrayed high-throughput screens.Splicing stimulates siRNA formation at Drosophila DNA double-strand breaks.Cytokine Diedel and a viral homologue suppress the IMD pathway in Drosophila.Cdk12 Is A Gene-Selective RNA Polymerase II Kinase That Regulates a Subset of the Transcriptome, Including Nrf2 Target Genes.
P50
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researcher
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M Boutros
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M Boutros
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M Boutros
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M Boutros
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M Boutros
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M Boutros
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P106
P31
P496
0000-0002-9458-817X