about
TRF2 and apollo cooperate with topoisomerase 2alpha to protect human telomeres from replicative damageNeonatal expression of RNA-binding protein IGF2BP3 regulates the human fetal-adult megakaryocyte transition.Single-chain antibodies that target lentiviral vectors to MHC class II on antigen-presenting cells.RUNX1-dependent RAG1 deposition instigates human TCR-δ locus rearrangementViability and stress protection of chronic lymphoid leukemia cells involves overactivation of mitochondrial phosphoSTAT3Ser727.Epitope dampening monotypic measles virus hemagglutinin glycoprotein results in resistance to cocktail of monoclonal antibodies.Improved lentiviral vectors for Wiskott-Aldrich syndrome gene therapy mimic endogenous expression profiles throughout haematopoiesis.Stem cell gene therapy for fanconi anemia: report from the 1st international Fanconi anemia gene therapy working group meeting.High levels of SOX5 decrease proliferative capacity of human B cells, but permit plasmablast differentiation.Surface-engineering of lentiviral vectors.Advances in foamy virus vector technology and disease correction could speed the path to clinical applicationStem cell factor-displaying simian immunodeficiency viral vectors together with a low conditioning regimen allow for long-term engraftment of gene-marked autologous hematopoietic stem cells in macaques.Lentiviral vectors displaying modified measles virus gp overcome pre-existing immunity in in vivo-like transduction of human T and B cells.Targeting IRAK1 in T-cell acute lymphoblastic leukemiaHaploinsufficiency for NR3C1, the gene encoding the glucocorticoid receptor, in blastic plasmacytoid dendritic cell neoplasms.Surface engineering of lentiviral vectors for gene transfer into gene therapy target cells.Gene Therapy in Fanconi anemia: a matter of time, safety and gene transfer tool efficiency.A Lentiviral Vector Allowing Physiologically Regulated Membrane-anchored and Secreted Antibody Expression Depending on B-cell Maturation Status.Exclusive Transduction of Human CD4+ T Cells upon Systemic Delivery of CD4-Targeted Lentiviral Vectors.GAPDH enhances the aggressiveness and the vascularization of non-Hodgkin's B lymphomas via NF-κB-dependent induction of HIF-1α.Baboon envelope pseudotyped LVs outperform VSV-G-LVs for gene transfer into early-cytokine-stimulated and resting HSCs.Measles virus glycoprotein-pseudotyped lentiviral vector-mediated gene transfer into quiescent lymphocytes requires binding to both SLAM and CD46 entry receptors.The DNA Damage Response Regulates RAG1/2 Expression in Pre-B Cells through ATM-FOXO1 Signaling.Triggering the TCR Developmental Checkpoint Activates a Therapeutically Targetable Tumor Suppressive Pathway in T-cell Leukemia.A novel lentiviral vector targets gene transfer into human hematopoietic stem cells in marrow from patients with bone marrow failure syndrome and in vivo in humanized mice.Hematopoietic stem cell targeting with surface-engineered lentiviral vectors.Efficient and stable transduction of resting B lymphocytes and primary chronic lymphocyte leukemia cells using measles virus gp displaying lentiviral vectors.Stable transduction of quiescent T cells without induction of cycle progression by a novel lentiviral vector pseudotyped with measles virus glycoproteins.High SYK Expression Drives Constitutive Activation of CD21low B Cells.A new generation of retroviral producer cells: predictable and stable virus production by Flp-mediated site-specific integration of retroviral vectors.Epigenetic silencing and tissue independent expression of a novel tetracycline inducible system in double-transgenic pigs.Baboon envelope pseudotyped lentiviral vectors efficiently transduce human B cells and allow active factor IX B cell secretion in vivo in NOD/SCIDγc-/- mice.Efficient gene transfer into human primary blood lymphocytes by surface-engineered lentiviral vectors that display a T cell-activating polypeptide.Human monocyte recognition of adenosine-based cyclic dinucleotides unveils the A2a Gαs protein-coupled receptor tonic inhibition of mitochondrially induced cell death.Low carbohydrate diet prevents Mcl-1-mediated resistance to BH3-mimeticsMutations in the H, F, or M Proteins Can Facilitate Resistance of Measles Virus to Neutralizing Human Anti-MV Sera.CD19 and CD20 targeted vectors induce minimal activation of resting B lymphocytes.Gene therapy for Fanconi anemia: one step closer to the clinic.Cytomegalovirus early promoter induced expression of hCD59 in porcine organs provides protection against hyperacute rejection.Evaluation of retroviral vector design in defined chromosomal loci by Flp-mediated cassette replacement.
P50
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P50
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researcher
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wetenschapper
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Els Verhoeyen
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Verhoeyen E
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Els Verhoeyen
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Verhoeyen E
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Verhoeyen E
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Els Verhoeyen
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Verhoeyen E
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P106
P31
P496
0000-0001-9224-5491