about
Arsenic exposure accelerates atherogenesis in apolipoprotein E-/-miceFirst-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3GDetyrosinated microtubules modulate mechanotransduction in heart and skeletal muscleImmunodetection of human topoisomerase I-DNA covalent complexesStructural insights into mechanisms of catalysis and inhibition in Norwalk virus polymeraseCovalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition ReactionsEPI-001 is a selective peroxisome proliferator-activated receptor-gamma modulator with inhibitory effects on androgen receptor expression and activity in prostate cancerSmall-molecule APOBEC3G DNA cytosine deaminase inhibitors based on a 4-amino-1,2,4-triazole-3-thiol scaffold.Oxidative Reactivities of 2-Furylquinolines: Ubiquitous Scaffolds in Common High-Throughput Screening Libraries.Lethal mutagenesis of poliovirus mediated by a mutagenic pyrimidine analogue.Synthesis and antiviral activity of 5-substituted cytidine analogues: identification of a potent inhibitor of viral RNA-dependent RNA polymerases.The Binding Interface between Human APOBEC3F and HIV-1 Vif Elucidated by Genetic and Computational Approaches.Lethal mutagenesis of picornaviruses with N-6-modified purine nucleoside analogues.Solution-phase synthesis of pyrrole-imidazole polyamidesStructural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B.Cell surface markers of cancer stem cells: diagnostic macromolecules and targets for drug delivery.Reassessing APOBEC3G Inhibition by HIV-1 Vif-Derived Peptides.Synthesis and antileukemic activities of C1-C10-modified parthenolide analogues.Parthenolide prodrug LC-1 slows growth of intracranial glioma.Alkyne Ligation Handles: Propargylation of Hydroxyl, Sulfhydryl, Amino, and Carboxyl Groups via the Nicholas ReactionA redox economical synthesis of bioactive 6,12-guaianolides.Catch and Release DNA Decoys: Capture and Photochemical Dissociation of NF-κB Transcription Factors.Synthesis of a peptide-universal nucleotide antigen: towards next-generation antibodies to detect topoisomerase I-DNA covalent complexes.Rapid, Microwave Accelerated Synthesis of [1,2,4]Triazolo[3,4-b][1,3,4]oxadiazoles from 4-Acylamino-1,2,4-Triazoles.Inhibition of guanosine monophosphate synthetase by the substrate enantiomer L-XMP.Synthesis and antiviral evaluation of a mutagenic and non-hydrogen bonding ribonucleoside analogue: 1-beta-D-Ribofuranosyl-3-nitropyrrole.APOBEC Enzymes as Targets for Virus and Cancer Therapy.Signatures of Nucleotide Analog Incorporation by an RNA-Dependent RNA Polymerase Revealed Using High-Throughput Magnetic Tweezers.Helenalin Analogues Targeting NF-κB p65: Thiol Reactivity and Cellular Potency Studies of Varied Electrophiles.Targeting NF-κB p65 with a Helenalin Inspired Bis-electrophile.SN-38 conjugated gold nanoparticles activated by Ewing sarcoma specific mRNAs exhibit in vitro and in vivo efficacy.Molecular Basis for the N-Terminal Bromodomain-and-Extra-Terminal-Family Selectivity of a Dual Kinase-Bromodomain InhibitorInhibiting APOBEC3 Activity with Single-Stranded DNA Containing 2'-Deoxyzebularine Analogues4-Cyanoindole-2'-deoxyribonucleoside (4CIN): A Universal Fluorescent Nucleoside AnalogueDifferential Inhibition of APOBEC3 DNA-Mutator Isozymes by Fluoro- and Non-Fluoro-Substituted 2'-Deoxyzebularine Embedded in Single-Stranded DNADeterminants of Oligonucleotide Selectivity of APOBEC3B
P50
Q23919503-AFD3B62F-8410-4F0A-BA1F-C3E9EB4DA900Q24615552-883909D9-9BC5-40A1-A1F9-B40BF292CBE2Q27321531-57AABBA2-F5A4-436E-9558-5246A6B7B33DQ27324108-7EE00C4B-CA0C-4DD1-829F-22DC5AB81105Q27649505-41DD13CD-0FF3-4A6B-977C-793BD547A8D5Q29248430-A1FAFD96-BCC3-4D77-945B-E7698BBDF3F3Q34462138-53270FB2-D50F-4913-B320-935E3B5D5E8DQ34488163-567BF36F-67B0-4766-B74E-036DFC8E40FAQ35769766-935A7406-275B-474A-8FB1-B0FDF5102620Q36099285-2D2151A4-42EA-42D9-8234-60806B69C5B0Q36168999-A4473AB3-052B-4E8A-B381-AE5D6FDE7756Q36384317-85F1BBF2-9586-4754-9322-282B51E58B5BQ36482715-BA174227-E1DF-4E52-AD80-C70ADF764632Q37209301-01A87E79-B37E-4A2D-A0DA-8981FDB6CC39Q37629738-C02586EE-9810-478E-BCC3-92F032251A4CQ38383345-59D12D10-FFF3-4E3C-BF97-07089B20DBFCQ38790689-F1A0B627-45E7-45C4-B79C-ED80271AB5CDQ38862410-34FD562D-5DB1-4162-A356-98AA085AC1FCQ38874373-E1C21D65-9281-40F8-9928-E656987FEC47Q41728863-0266CE60-2BAA-4824-9DF8-2105D3166F70Q41892002-3686E54A-79DA-4E97-A802-4D37AD267802Q42034857-B4BA2139-AEE7-4633-ABAF-1436C9971DB0Q42072372-292D285D-745D-490B-8A70-BCBF49AFA6D7Q42207765-7C8D616E-CF0A-43D6-849C-808BD75B976FQ42562410-12BC6607-F235-45DA-B326-F191543B0C81Q44064718-1F7EB14F-BC34-4B05-A268-B55A4D091E1FQ45324625-3188ACAD-8003-4668-B24D-CFC08B73FF76Q47158736-0D3B3D42-4B41-4AFD-8FBC-793B91019FA4Q48211122-E412FE0C-ADA3-4425-91E6-42A3B3EC7588Q48333812-78627FA7-51DA-45C2-816C-BE1B1AF96961Q50141262-E7BF7919-8457-48D8-9349-A0AF2767D668Q57787498-E01B05AF-E1E0-4B46-B5E2-B55F8BF734C6Q59351278-CA8721D7-BD6E-4CEC-B674-171624B1E593Q89496225-B66728BB-31B6-48FB-9C78-E832CC74D4BBQ90842351-86357E06-E986-4466-BEE4-68DBEE685D4AQ91061839-BC6A969A-5F2C-4B28-A933-CD7928103258
P50
description
researcher
@en
wetenschapper
@nl
name
Daniel A Harki
@en
Daniel A Harki
@es
Daniel A Harki
@nl
type
label
Daniel A Harki
@en
Daniel A Harki
@es
Daniel A Harki
@nl
prefLabel
Daniel A Harki
@en
Daniel A Harki
@es
Daniel A Harki
@nl
P106
P31
P496
0000-0001-5950-931X