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An efficient system for intracellular delivery of beta-lactam antibiotics to overcome bacterial resistanceBiological study of the effect of water soluble [N-(2-hydroxybenzyl)-L-aspartato] gallium complexes on breast carcinoma and fibrosarcoma cells.Effects of siRNA on RET/PTC3 junction oncogene in papillary thyroid carcinoma: from molecular and cellular studies to preclinical investigationsTranslocation of poly(ethylene glycol-co-hexadecyl)cyanoacrylate nanoparticles into rat brain endothelial cells: role of apolipoproteins in receptor-mediated endocytosis.Analysis of plasma protein adsorption onto PEGylated nanoparticles by complementary methods: 2-DE, CE and Protein Lab-on-chip system.A comprehensive study of the spontaneous formation of nanoassemblies in water by a "lock-and-key" interaction between two associative polymers.Therapeutic modalities of squalenoyl nanocomposites in colon cancer: an ongoing search for improved efficacyLinker-modified quinoline derivatives targeting HIV-1 integrase: synthesis and biological activity.Novel self assembling nanoparticles for the oral administration of fondaparinux: synthesis, characterization and in vivo evaluation.Lipid-Conjugation of Endogenous Neuropeptides: Improved Biotherapy against Human Pancreatic Cancer.Antineoplastic Effects of siRNA against TMPRSS2-ERG Junction Oncogene in Prostate Cancer.Turning Squalene into Cationic Lipid Allows a Delivery of siRNA in Cultured CellsAntitumor activity of a rhenium (I)-diselenoether complex in experimental models of human breast cancerA Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of Human Respiratory Syncytial VirusKnocking Down TMPRSS2-ERG Fusion Oncogene by siRNA Could be an Alternative Treatment to FlutamideChemistry and structure-activity relationship of the styrylquinoline-type HIV integrase inhibitors.Squalenoylation: a generic platform for nanoparticular drug delivery.Lipid conjugated oligonucleotides: a useful strategy for delivery.X-ray microfluorescence for biodistribution studies of nanomedicines.Dose Effect of Rhenium (I)-diselenoether as Anticancer Drug in Resistant Breast Tumor-bearing Mice After Repeated Administrations."Squalenoylcurcumin" nanoassemblies as water-dispersible drug candidates with antileishmanial activity.Osteotropic polypeptide nanoparticles with dual hydroxyapatite binding properties and controlled cisplatin delivery.Gemcitabine-based therapy for pancreatic cancer using the squalenoyl nucleoside monophosphate nanoassemblies.Self-assembly of polyisoprenoyl gemcitabine conjugates: influence of supramolecular organization on their biological activity.Uptake and efflux of rhenium in cells exposed to rhenium diseleno-ether and tissue distribution of rhenium and selenium after rhenium diseleno-ether treatment in mice.Nanotechnologies for the treatment of colon cancer: From old drugs to new hope.Effects of silencing the RET/PTC1 oncogene in papillary thyroid carcinoma by siRNA-squalene nanoparticles with and without fusogenic companion GALA-cholesterol.Polymer prodrug nanoparticles based on naturally occurring isoprenoid for anticancer therapy.Improving the antitumor activity of squalenoyl-paclitaxel conjugate nanoassemblies by manipulating the linker between paclitaxel and squalene.Polyisoprenoyl gemcitabine conjugates self assemble as nanoparticles, useful for cancer therapy.Combination of three metals for the treatment of cancer: gallium, rhenium and platinum. 1. Determination of the optimal schedule of treatment.Self-assembled squalenoylated penicillin bioconjugates: an original approach for the treatment of intracellular infections.The role of solvent swelling in the self-assembly of squalene based nanomedicines.Synthesis, characterization, and in vivo delivery of siRNA-squalene nanoparticles targeting fusion oncogene in papillary thyroid carcinoma.Squalene based nanocomposites: a new platform for the design of multifunctional pharmaceutical theragnostics.Squalenoyl nucleoside monophosphate nanoassemblies: new prodrug strategy for the delivery of nucleotide analogues.Anticancer efficacy of squalenoyl gemcitabine nanomedicine on 60 human tumor cell panel and on experimental tumor.Squalenoyl nanomedicine of gemcitabine is more potent after oral administration in leukemia-bearing rats: study of mechanisms.A new nanomedicine of gemcitabine displays enhanced anticancer activity in sensitive and resistant leukemia types.Circulating Lipoproteins: A Trojan Horse Guiding Squalenoylated Drugs to LDL-Accumulating Cancer Cells.
P50
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P50
name
Didier Desmaële
@en
Didier Desmaële
@nl
type
label
Didier Desmaële
@en
Didier Desmaële
@nl
prefLabel
Didier Desmaële
@en
Didier Desmaële
@nl