about
sameAs
P688
TGF-beta signal transductionType III TGF-beta receptor-independent signalling of TGF-beta2 via TbetaRII-B, an alternatively spliced TGF-beta type II receptorSmurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradationCholesterol suppresses cellular TGF-beta responsiveness: implications in atherogenesisInteraction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-beta receptor complexMyostatin signals through a transforming growth factor beta-like signaling pathway to block adipogenesisExtracellular and cytoplasmic domains of endoglin interact with the transforming growth factor-beta receptors I and IIRegulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticitySB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7SB-431542 and Gleevec inhibit transforming growth factor-beta-induced proliferation of human osteosarcoma cellsThe type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent mannerMADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signalingDual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexesTransforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumabEndoglin phosphorylation by ALK2 contributes to the regulation of prostate cancer cell migrationTGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinomaIncrease in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and miceReceptor-associated Mad homologues synergize as effectors of the TGF-beta responseEndoglin is a component of the transforming growth factor-beta receptor system in human endothelial cellsTGF beta signals through a heteromeric protein kinase receptor complexSyntenin regulates TGF-β1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-β type I receptor internalizationRegulation and function of miR-214 in pulmonary arterial hypertension.APPL proteins promote TGFβ-induced nuclear transport of the TGFβ type I receptor intracellular domain.
P921
Q22003891-3CCBFA80-5345-442E-97B4-E10588B374B6Q24290737-25CB08A6-06E3-4650-A8D7-9701AD037D31Q24291000-33833CF9-6D5A-4D5E-BB4E-C6119A43FDC9Q24294300-109B9BC7-5E0D-4CC3-BBE9-9267C71B7372Q24294521-CCD3CAB2-1F01-4709-8ED2-F34E59F2773EQ24296422-086F96F1-9CC6-473E-8777-B732B6B749BBQ24297609-FB0049C3-3D65-4470-B027-72AE52AEE182Q24297858-BA2CAECC-E9B7-4D89-B502-84966816EB31Q24299813-934F0616-7285-4A0E-AA90-CD34769CD7E6Q24300308-26AF715C-1B50-4927-BE74-25778A786C73Q24308947-A1F94808-F20B-4F7C-B0D7-006460A26849Q24310282-4B35A57A-45FF-4464-BBB1-3A50FF8A3962Q24310852-4E22B2D0-69F0-4028-914E-7F27F3B269A6Q24313194-63C53D44-9BF9-440F-9C85-5F1ABB304EF9Q24314139-88B96987-CBAB-4818-83A7-0E0B2350393CQ24314661-2087938C-1C49-433B-B8E5-683158C8D589Q24315119-67174325-815C-4B9D-A1C6-05C985E1CCDFQ24316877-6CBA1113-7075-4CEA-B6B8-2584EB59028FQ24318330-6F6D0925-BB35-478A-90D4-797FC37810CCQ24337230-5C381095-8C65-4206-9A7D-4F20616BF86DQ24337608-A0D6C55A-AD44-4D8B-9224-8088076BD007Q28118751-80A784ED-5891-4E22-9DF2-810F2E8592E4Q32884388-DD554B9D-B697-43C9-B6F9-7A46B83B7C40Q36729386-A3737AD9-A4C2-4FE1-9CC9-C3C2847D79B0
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Transforming growth factor beta receptor 1
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
Receptor de TGF-beta 1
@es
Transforming growth factor beta receptor 1
@en
Transforming growth factor beta receptor 1
@nl
type
label
Receptor de TGF-beta 1
@es
Transforming growth factor beta receptor 1
@en
Transforming growth factor beta receptor 1
@nl
altLabel
ALK-5
@en
ALK5
@en
Receptor de TGF beta 1
@es
SKR4
@en
TGF-beta receptor type I
@en
TGF-beta receptor type-1
@en
TGF-beta type I receptor
@en
TGFBR1
@en
TbetaR-I
@en
activin A receptor type II-like kinase, 53kDa
@en
prefLabel
Receptor de TGF-beta 1
@es
Transforming growth factor beta receptor 1
@en
Transforming growth factor beta receptor 1
@nl
P527
P637
P638
P680
P681
P682
P705
P352
P31
P352
P527
P637
NP_001124388
NP_001293139
XP_011517250
XP_011517251
XP_011517252
XP_016870552
XP_024303426
P638
P680
P681
P682
P702
P703
P705
ENSP00000364129
ENSP00000364133
ENSP00000446685
ENSP00000447182
ENSP00000447297
ENSP00000447707
ENSP00000448518
ENSP00000449028
ENSP00000449934
ENSP00000450052