about
The cell nucleus and aging: tantalizing clues and hopeful promisesUbiquitination regulates PTEN nuclear import and tumor suppressionTDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expressionA cyclophilin functions in pre-mRNA splicingReversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndromeEpigenetics in alternative pre-mRNA splicingLamin A-dependent misregulation of adult stem cells associated with accelerated ageingHuman chromokinesin KIF4A functions in chromosome condensation and segregationCondensed mitotic chromatin is accessible to transcription factors and chromatin structural proteinsLamin A-dependent nuclear defects in human agingA non-random walk through the genomeTissue-specific spatial organization of genomesDifferential recruitment of pre-mRNA splicing factors to alternatively spliced transcripts in vivo.Not All DDRs Are Created Equal: Non-Canonical DNA Damage ResponsesCommon features of chromatin in aging and cancer: cause or coincidence?Release of chromatin protein HMGB1 by necrotic cells triggers inflammationAberrant nuclear trafficking of La protein leads to disordered processing of associated precursor tRNAs
P50
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P50
description
Swiss biologist
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Tom Misteli
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Tom Misteli
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Tom Misteli
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Tom Misteli
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Tom Misteli
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Tom Misteli
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Tom Misteli
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Tom Misteli
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