about
HIV-1 infection in infants severely impairs the immune response induced by Bacille Calmette-Guérin vaccine.Maturation of innate responses to mycobacteria over the first nine months of life.The novel tuberculosis vaccine, AERAS-402, induces robust and polyfunctional CD4+ and CD8+ T cells in adults.Association of human TLR1 and TLR6 deficiency with altered immune responses to BCG vaccination in South African infants.Novel application of Ki67 to quantify antigen-specific in vitro lymphoproliferation.Patients with tuberculosis disease have Mycobacterium tuberculosis-specific CD8 T cells with a pro-apoptotic phenotype and impaired proliferative capacity, which is not restored following treatment.Functional capacity of Mycobacterium tuberculosis-specific T cell responses in humans is associated with mycobacterial loadA phase IIa trial of the new tuberculosis vaccine, MVA85A, in HIV- and/or Mycobacterium tuberculosis-infected adultsHigher human CD4 T cell response to novel Mycobacterium tuberculosis latency associated antigens Rv2660 and Rv2659 in latent infection compared with tuberculosis disease.Longitudinal changes in CD4(+) T-cell memory responses induced by BCG vaccination of newborns.Lessons learnt from the first efficacy trial of a new infant tuberculosis vaccine since BCG.Induction and regulation of T-cell immunity by the novel tuberculosis vaccine M72/AS01 in South African adults.Significantly skewed memory CD8+ T cell subsets in HIV-1 infected infants during the first year of life.HIV-1 Infection Is Associated with Depletion and Functional Impairment of Mycobacterium tuberculosis-Specific CD4 T Cells in Individuals with Latent Tuberculosis Infection.Application of a whole blood mycobacterial growth inhibition assay to study immunity against Mycobacterium tuberculosis in a high tuberculosis burden population.Optimization of a whole blood intracellular cytokine assay for measuring innate cell responses to mycobacteria.The novel tuberculosis vaccine, AERAS-402, is safe in healthy infants previously vaccinated with BCG, and induces dose-dependent CD4 and CD8T cell responses.Dose-finding study of the novel tuberculosis vaccine, MVA85A, in healthy BCG-vaccinated infants.PD-1 Expression on -Specific CD4 T Cells Is Associated With Bacterial Load in Human Tuberculosis
P50
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P50
name
Marwou de Kock
@en
Marwou de Kock
@nl
type
label
Marwou de Kock
@en
Marwou de Kock
@nl
prefLabel
Marwou de Kock
@en
Marwou de Kock
@nl