about
Acid-mediated cleavage of oligonucleotide P3' --> N5' phosphoramidates triggered by sequence-specific triplex formation.Synthesis of novel cationic spermine-conjugated phosphotriester oligonucleotide for improvement of cell membrane permeability.Gene silencing by 2'-O-methyldithiomethyl-modified siRNA, a prodrug-type siRNA responsive to reducing environment.Cellular uptake and intracellular trafficking of antisense and siRNA oligonucleotides.Conjugation with receptor-targeted histidine-rich peptides enhances the pharmacological effectiveness of antisense oligonucleotidesEffect of Ala replacement with Aib in amphipathic cell-penetrating peptide on oligonucleotide delivery into cells.Targeted intracellular delivery of antisense oligonucleotides via conjugation with small-molecule ligands.The chemistry and biology of oligonucleotide conjugates.The spermine-bisaryl conjugate as a potent inducer of B- to Z-DNA transition.Covalent conjugation of oligonucleotides with cell-targeting ligands.Selective fluorescence quenching of the 8-oxoG-clamp by 8-oxodeoxyguanosine in ODN.Synthesis and thermal stabilities of oligonucleotides containing 2'-O,4'-C-methylene bridged nucleic acid with a phenoxazine base.RGD Conjugated Dendritic Polylysine for Cellular Delivery of Antisense Oligonucleotide.Regulated incorporation of two different metal ions into programmed sites in a duplex by DNA polymerase catalyzed primer extension.Ag(I) ion mediated formation of a C-A mispair by DNA polymerases.Synthesis and properties of a novel bridged nucleic acid with a P3' --> N5' phosphoramidate linkage, 5'-amino-2',4'-BNASpecific fluorescent probe for 8-oxoguanosineDouble-stranded DNA-templated oligonucleotide digestion triggered by triplex formationPresence of 2',5'-linkages in a homopyrimidine DNA oligonucleotide promotes stable triplex formation under physiological conditionsPromotion of stable triplex formation by partial incorporation of 2',5'-phosphodiester linkages into triplex-forming oligonucleotides[Development of artificial nucleic acids functionalized for damaged gene diagnosis, gene inhibition and delivery system]A New Nucleic Acid Prodrug Responsive to High Thiol Concentration: Synthesis of 2'-O-Methyldithiomethyl-Modified Oligonucleotides by Post-Synthetic ModificationEffective gene silencing activity of prodrug-type 2'-O-methyldithiomethyl siRNA compared with non-prodrug-type 2'-O-methyl siRNAOligonucleotides Containing Phenoxazine Artificial Nucleobases: Triplex-Forming Abilities and Fluorescence Properties2'-O,4'-C-Methylene-Bridged Nucleic Acids Stabilize Metal-Mediated Base Pairing in a DNA Duplex1,3,9-Triaza-2-oxophenoxazine: An Artificial Nucleobase Forming Highly Stable Self-Base Pairs with Three AgI Ions in a DuplexSilver(I)-Ion-Mediated Cytosine-Containing Base Pairs: Metal Ion Specificity for Duplex Stabilization and Susceptibility toward DNA Polymerases
P50
Q33308518-860E39A2-DEF3-49B0-9A23-AF1B23472C3FQ35684603-48D92B67-3382-41EE-9EF6-0E347ED70DF5Q35891343-4420CFAF-7E34-4A63-B458-164F2279DCD0Q37944929-FDB6C719-C84F-4319-B799-6C34DD2BEF20Q39041906-8F260F1D-D422-4F06-9D82-0503259BDB83Q39064574-78F1AC60-F9A4-4CE3-A16C-5226D42D7B82Q39692815-03F174B4-AB3F-4168-BB6A-5D30493BEACFQ42011018-A29B5C5E-EDBB-40C8-877C-8EFCB69992D6Q42912653-9A15E88E-1BFE-4496-963B-FA1EA76B2B11Q42958209-987C61D3-48A4-489B-BF63-D359410E957DQ46182277-896B3ADE-3F45-4A4F-89F1-94BC68846622Q50050836-C1E50364-4A7A-4A85-80CD-7F983CC629D0Q52325222-A69BB28E-DAB4-4968-B21E-5CDECD479F92Q54361091-1D999CA1-7067-49C1-93DB-565CE49E6EC3Q54508159-35BA715B-9465-4DE8-A19B-E197D1729E58Q78755201-501178C8-DDBA-4F8B-BA3E-6F0DEE917C87Q80306466-31C88CB4-C583-4BBE-A71C-B804FC6DC031Q81294609-ED559620-AA5A-4FD4-A467-C4DA8B292893Q81400160-7A342D5B-2F22-48E8-A55D-A8C6A034CFF6Q81803472-2122AA5C-BC8C-4A72-8E20-87A864EE61E2Q86118999-82E2ADCD-FCF2-4623-8D0B-EB4BB9DA1407Q86182567-E8C3743B-298B-4EEA-B79A-FC883E057949Q88682851-48237EB0-C867-43F1-A3D6-8DCE4316BC71Q90376427-23734F8A-057B-4F98-85BB-C1F659FC4A05Q91247791-EF36EEE5-106B-4F41-A6E7-CA25C9770521Q92184266-04718CAD-91D1-4936-949D-E78EDBFBFE01Q92951636-AC0EDACA-834F-4BB8-A0FE-D0FE2682E8CE
P50
description
Forscher
@de
investigador
@es
onderzoeker
@nl
researcher
@en
ricercatore
@it
研究員
@ja
研究者
@zh
name
Osamu Nakagawa
@en
Osamu Nakagawa
@nl
type
label
Osamu Nakagawa
@en
Osamu Nakagawa
@nl
prefLabel
Osamu Nakagawa
@en
Osamu Nakagawa
@nl
P106
P31
P496
0000-0001-5412-3530