about
Trans,trans,trans-[PtIV(N3)2(OH)2(py)(NH3)]: a light-activated antitumor platinum complex that kills human cancer cells by an apoptosis-independent mechanism.Photoactivated chemotherapy (PACT): the potential of excited-state d-block metals in medicine.De novo generation of singlet oxygen and ammine ligands by photoactivation of a platinum anticancer complex.Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts.Interactions of DNA with a new platinum(IV) azide dipyridine complex activated by UVA and visible light: relationship to toxicity in tumor cells.A potent trans-diimine platinum anticancer complex photoactivated by visible light.Synthesis, characterisation and photochemistry of Pt(IV) pyridyl azido acetato complexes.Probing platinum azido complexes by 14N and 15N NMR spectroscopy.Photo-isomerisation of alkenyl complexes of platinum(II): structural, spectroscopic, kinetic and computational investigations.A computational approach to tuning the photochemistry of platinum(IV) anticancer agents.Platinum(iv) azido complexes undergo copper-free click reactions with alkynes.Proton sponge phosphines: electrospray-active ligandsPhotochemistry in photonic crystal fiber nanoreactorsMicrofluidic integration of photonic crystal fibers for online photochemical reaction analysisCombined theoretical and computational study of interstrand DNA guanine-guanine cross-linking by trans-[Pt(pyridine)2] derived from the photoactivated prodrug trans,trans,trans-[Pt(N3)2(OH)2(pyridine)2]Two-photon-activated ligand exchange in platinum(II) complexesEnhancing 31P NMR relaxation rates with a kinetically inert gadolinium complexA novel Pt(iv) mono azido mono triazolato complex evolves azidyl radicals following irradiation with visible lightPlatinum(iv) dihydroxido diazido N-(heterocyclic)imine complexes are potently photocytotoxic when irradiated with visible lightOxaliplatin and [Pt(R,R-DACH)(panobinostat-2H)] show nanomolar cytotoxicity towards diffuse intrinsic pontine glioma (DIPG)INDIANA: An in-cell diffusion method to characterize the size, abundance and permeability of cells
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description
researcher ORCID ID=0000-0002-7440-1291
@en
name
Nicola J Farrer
@en
Nicola J Farrer
@nl
type
label
Nicola J Farrer
@en
Nicola J Farrer
@nl
prefLabel
Nicola J Farrer
@en
Nicola J Farrer
@nl
P106
P31
P496
0000-0002-7440-1291