about
Thieno[3,2-c]pyrazoles: a novel class of Aurora inhibitors with favorable antitumor activityS2RSLDB: a comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands5-HT7 receptor ligands: recent developments and potential therapeutic applications.Serotonin 5-HT3 and 5-HT4 ligands: an update of medicinal chemistry research in the last few years.Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors.Antitumor properties of substituted (αE)-α-(1H-indol-3-ylmethylene)benzeneacetic acids or amides.Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties.Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions.Role of the Nrf2/HO-1 axis in bronchopulmonary dysplasia and hyperoxic lung injuries.New bifunctional antioxidant/σ1 agonist ligands: Preliminary chemico-physical and biological evaluation.Novel 4-phenylpiperidine-2,6-dione derivatives. Ligands for α₁-adrenoceptor subtypes.New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: analogues of HEAT as ligands for the alpha1-adrenergic receptor subtypes.3-Amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: a new class of CDK2 inhibitors.Effects of novel hybrids of caffeic acid phenethyl ester and NSAIDs on experimental ocular inflammation.Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitorsRecent advances in drug discovery of phototherapeutic non-porphyrinic anticancer agents.Synthesis of 3-arylpiperazinylalkylpyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as novel, potent, and selective alpha1-adrenoceptor ligands.Effects of Novel Nitric Oxide-Releasing Molecules against Oxidative Stress on Retinal Pigmented Epithelial Cells.Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole derivatives as potent and selective 5-HT1A serotonin receptor ligands.A facile synthesis of new 2-carboxamido-3-carboxythiophene and 4,5,6,7-tetrahydro-2-carboxamido-3-carboxythieno[2,3-c]pyridine derivatives as potential endothelin receptors ligands.Synthesis and endothelin receptor binding affinity of a novel class of 2-substituted-4-aryl-3-quinolinecarboxylic acid derivatives.3-Arylpiperazinylethyl-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione derivatives as novel, high-affinity and selective alpha(1)-adrenoceptor ligands.Synthesis of 1,2,4-triazole derivatives: binding properties on endothelin receptors.(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties.Novel Sigma-1 receptor antagonists: from opioids to small molecules: what is new?Novel Sigma Receptor Ligand-Nitric Oxide Photodonors: Molecular Hybrids for Double-Targeted Antiproliferative Effect.Synthesis and evaluation of haloperidol metabolite II prodrugs as anticancer agents.Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands.Nrf2 as regulator of innate immunity: A molecular Swiss army knife!Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors.Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands.Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-1.New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT7 and 5-HT1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies.Design and synthesis of new homo and hetero bis-piperazinyl-1-propanone derivatives as 5-HT7R selective ligands over 5-HT1AR.Synthesis and endothelin receptors binding affinity of new 1,3,5- substituted pyrrole-2-carboxylic acid derivatives.Identification of potentially potent Heme Oxygenase-1 inhibitors through 3D-QSAR coupled to scaffold hopping analysis.Heme oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia.High affinity ligands and potent antagonists for the α1D-adrenergic receptor. Novel 3,8-disubstituted [1]benzothieno[3,2-d]pyrimidine derivatives.Novel imidazole derivatives as heme oxygenase-1 (HO-1) and heme oxygenase-2 (HO-2) inhibitors and their cytotoxic activity in human-derived cancer cell lines.Structure–activity relationships and molecular modeling studies of novel arylpiperazinylalkyl 2-benzoxazolones and 2-benzothiazolones as 5-HT7 and 5-HT1A receptor ligands
P50
Q27664271-DE274229-3FFE-4946-8137-DEB1086E8A41Q28818635-3AC7FC3B-85D6-4596-87E9-40E9E511B65CQ34693538-99DF5B0C-DA77-4E11-B3FE-045C0E7AE252Q37656446-2A96E335-13D3-45CE-A3D8-E945E5311AAFQ38679172-EE5D4BB6-0F4F-4BB6-B1E1-DAF490926A9BQ39123183-D6CD3306-6FF1-4971-91DA-D9D5D794938AQ39124032-18EBE0D3-1888-450E-A0E0-E9CFDA2E6945Q39376128-4706C80D-37E9-4352-9496-FF11EBE24E42Q39408026-63DCE84C-9D57-4F7C-8852-6337E0F1C373Q39709628-ABD49E9E-DBD1-4575-BA52-91FC7C9E2717Q39757730-B982F6ED-E40F-4870-A4F7-E56448995BF5Q40285918-F6737CF9-6365-43A6-BB89-C6895691854EQ40350772-C150093A-90CA-4D43-AB4A-4345D789D9F4Q41371329-072F0009-01F6-4B09-9D2E-033050800DA9Q42374355-3CCA18D7-3E7F-498D-B333-0DD15F734327Q46301617-EC7337C3-9A43-4A0C-A642-780AEFC3562AQ46414054-64981419-D699-4C87-A324-9B76E489A873Q46470953-1CB05450-93AD-4229-B293-8B0F6AD5CA76Q46504572-9892C205-0756-43E7-BFAA-8FF7F7B6E266Q46615123-5DA4CC51-5A02-47B8-AD59-8421B83247AAQ46705944-61946FDF-36FA-4481-9B15-45B99BE8F93EQ46745428-3E055802-7C4D-48E4-B6B2-FDBD53616296Q46877150-7ED05BC9-5922-4016-A2FF-DA9E1A38DEA5Q47343721-726EC068-0350-438E-B7CB-57E9014E0D0BQ47353437-075256D5-B213-48EB-AD5B-AA732675C63DQ47367736-CFAEE972-8F78-4486-A0F0-3430B5D2B7C3Q47860855-2E47AFDB-ED6E-4776-8B29-60AE582EB227Q47864786-768292DD-6D11-4F4D-B038-D2EE74336462Q49580837-F3159743-F3CE-4F2B-ADD7-B7D7FA239120Q49902738-60ABCA30-9822-408E-BFC9-EDA1ED78F204Q50587426-04CC7EBF-43E3-4372-BBCC-9ECA673B989AQ50897437-CD2F05DF-85F0-4A40-9B7F-F0DCE1F67A95Q51210141-3F00A5E1-E055-45D0-A6F4-3AB38D2A8DFBQ51652163-0BD58EF0-4AA1-465C-8B89-D74E978BF962Q51746721-31048F92-4894-4E12-98AF-34585940C50AQ52564046-3BE91935-0717-452D-996D-F13D5DD6BC50Q53135203-5939CED6-2534-44F7-A487-DB5F2A158745Q53709851-CD8B542B-BAED-4432-9E98-30D076C5260DQ53803393-A14D6F05-8338-4075-93C7-6D410355C917Q56980046-60F93404-46BA-4443-8521-F417E26430F6
P50
description
researcher ORCID ID=0000-0003-1856-0308
@en
wetenschapper
@nl
name
Valeria Pittalà
@en
Valeria Pittalà
@nl
type
label
Valeria Pittalà
@en
Valeria Pittalà
@nl
prefLabel
Valeria Pittalà
@en
Valeria Pittalà
@nl
P106
P31
P496
0000-0003-1856-0308