about
FKBP12.6 binding of ryanodine receptors carrying mutations associated with arrhythmogenic cardiac diseaseFunctional heterogeneity of ryanodine receptor mutations associated with sudden cardiac death.Ryanodine receptor regulation by intramolecular interaction between cytoplasmic and transmembrane domains.Insights into the gating mechanism of the ryanodine-modified human cardiac Ca2+-release channel (ryanodine receptor 2).Ryanodine receptor mutations in arrhythmias: advances in understanding the mechanisms of channel dysfunction.Unambiguous observation of blocked states reveals altered, blocker-induced, cardiac ryanodine receptor gatingRyanodine receptor mutations in arrhythmia: The continuing mystery of channel dysfunction.Techniques and methodologies to study the ryanodine receptor at the molecular, subcellular and cellular level.Calsequestrin interacts directly with the cardiac ryanodine receptor luminal domain.Effect of flecainide derivatives on sarcoplasmic reticulum calcium release suggests a lack of direct action on the cardiac ryanodine receptor.Differential Ca2+ sensitivity of RyR2 mutations reveals distinct mechanisms of channel dysfunction in sudden cardiac death.The mechanism of flecainide action in CPVT does not involve a direct effect on RyR2.Questioning flecainide's mechanism of action in the treatment of catecholaminergic polymorphic ventricular tachycardia.Dantrolene rescues aberrant N-terminus intersubunit interactions in mutant pro-arrhythmic cardiac ryanodine receptors.Role of ryanodine receptor mutations in cardiac pathology: more questions than answers?Identification of an amino-terminus determinant critical for ryanodine receptor/Ca2+ release channel function
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Q24312162-2AABEEEF-267C-4B02-995C-6DF95738544BQ31111627-9A49EB78-13C0-4BA9-9FEF-EDE145ACBC83Q34359135-73A93425-DABC-403D-9817-262276519D0EQ34439508-0650C514-AD9D-45FF-86E1-E2B52CF65E22Q34705614-7D9BAC1E-575E-4850-860A-DAB66B77D5D5Q37310813-120557AA-0B31-4207-A478-6BE4C1290ADFQ37687548-778F136A-396C-455D-9AE9-54B562D74DB2Q37997674-ABB56C43-A494-45E5-A0C3-5F305FC02E4CQ38734361-33E4EFCD-F39D-49B0-A028-F7F96E5DBE2CQ39727420-4BAC66E5-1CE2-4CAF-87A7-72BE86EF89F0Q40432190-542D506D-53F3-47A1-B818-8B6779A05F77Q41484309-B92EDD40-018A-4EAD-B7CC-EC10254C5895Q42377056-B0F956C1-2813-4FA5-BF62-4D886CC2D0E9Q52655119-B5C7CB89-3CCE-45DE-98CC-9BDBC221321DQ79276363-38A7A424-D021-4BE0-B902-83CBB3E2D767Q89799576-E4B01C3B-3C28-4860-A1FC-BB4860D361FE
P50
description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Nia Lowri Thomas
@en
Nia Lowri Thomas
@nl
type
label
Nia Lowri Thomas
@en
Nia Lowri Thomas
@nl
altLabel
Thomas NL
@en
prefLabel
Nia Lowri Thomas
@en
Nia Lowri Thomas
@nl
P31
P496
0000-0001-8822-8576