about
Lengthening of mouse hindlimbs with joint loading.Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells.Salubrinal promotes healing of surgical wounds in rat femurs.Predicting and validating the pathway of Wnt3a-driven suppression of osteoclastogenesisKnee loading reduces MMP13 activity in the mouse cartilage.Salubrinal acts as a Dusp2 inhibitor and suppresses inflammation in anti-collagen antibody-induced arthritisChondroprotective effects of Salubrinal in a mouse model of osteoarthritis.MSC Transplantation Improves Osteopenia via Epigenetic Regulation of Notch Signaling in Lupus.Role of miR-222-3p in c-Src-Mediated Regulation of Osteoclastogenesis.Biosignals modulated by tumor-associated carbohydrate antigens: novel targets for cancer therapy.Trimeric Tn antigen on syndecan 1 produced by ppGalNAc-T13 enhances cancer metastasis via a complex formation with integrin α5β1 and matrix metalloproteinase 9.Molecules in the signaling pathway activated by gangliosides can be targets of therapeutics for malignant melanomas.Model-based comparative prediction of transcription-factor binding motifs in anabolic responses in bone.Potential applications of pulsating joint loading in sports medicine.α1B -Adrenoceptor signalling regulates bone formation through the up-regulation of CCAAT/enhancer-binding protein δ expression in osteoblasts.Disialyl gangliosides enhance tumor phenotypes with differential modalities.Reduction in Migratory Phenotype in a Metastasized Breast Cancer Cell Line via Downregulation of S100A4 and GRM3.Salubrinal improves mechanical properties of the femur in osteogenesis imperfecta mice.A therapeutic trial of human melanomas with combined small interfering RNAs targeting adaptor molecules p130Cas and paxillin activated under expression of ganglioside GD3.Suppressed invasive and migratory behaviors of SW1353 chondrosarcoma cells through the regulation of Src, Rac1 GTPase, and MMP13.Attenuation of malignant phenotypes of breast cancer cells through eIF2α-mediated downregulation of Rac1 signaling.Proteomic analysis of ganglioside-associated membrane molecules: substantial basis for molecular clustering.Enhancement of malignant properties of human osteosarcoma cells with disialyl gangliosides GD2/GD3.RhoA-mediated signaling in mechanotransduction of osteoblasts.pp-GalNAc-T13 induces high metastatic potential of murine Lewis lung cancer by generating trimeric Tn antigen.GM1 / GD1b / GA1 synthase expression results in the reduced cancer phenotypes with modulation of composition and raft-localization of gangliosides in a melanoma cell line.Systems analysis of bone remodelling as a homeostatic regulator.Essential roles of integrin-mediated signaling for the enhancement of malignant properties of melanomas based on the expression of GD3.Overexpression of caveolin-1 in a human melanoma cell line results in dispersion of ganglioside GD3 from lipid rafts and alteration of leading edges, leading to attenuation of malignant properties.Stress to endoplasmic reticulum of mouse osteoblasts induces apoptosis and transcriptional activation for bone remodeling.Guanabenz Downregulates Inflammatory Responses via eIF2α Dependent and Independent Signaling.Salubrinal reduces expression and activity of MMP13 in chondrocytes.Suppression of osteoclastogenesis through phosphorylation of eukaryotic translation initiation factor 2 alpha.In vitro and in silico analysis of an inhibitory mechanism of osteoclastogenesis by salubrinal and guanabenz.Bidirectional communication between sensory neurons and osteoblasts in an in vitro coculture system.Positive feedback loop between PI3K-Akt-mTORC1 signaling and the lipogenic pathway boosts Akt signaling: induction of the lipogenic pathway by a melanoma antigen.Suppression of osteoclastogenesis via α2-adrenergic receptors.Differential roles of gangliosides in malignant properties of melanomasNew era of research on cancer-associated glycosphingolipidsConditioned medium from rat dental pulp reduces the number of osteoclasts via attenuation of adhesiveness in osteoclast precursors
P50
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P50
description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Kazunori Hamamura
@en
Kazunori Hamamura
@nl
type
label
Kazunori Hamamura
@en
Kazunori Hamamura
@nl
prefLabel
Kazunori Hamamura
@en
Kazunori Hamamura
@nl
P31
P496
0000-0002-8143-338X