about
Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targetsBicyclic hydroxy-1H-pyrrolopyridine-trione containing HIV-1 integrase inhibitors.HIV integrase inhibitors block replication of alpha-, beta-, and gammaherpesvirusesHIV-1 Integrase Strand Transfer Inhibitors with Reduced Susceptibility to Drug Resistant Mutant IntegrasesComparison of metal-dependent catalysis by HIV-1 and ASV integrase proteins using a new and rapid, moderate throughput assay for joining activity in solution6,7-Dihydroxyisoindolin-1-one and 7,8-Dihydroxy-3,4-Dihydroisoquinolin- 1(2H)-one Based HIV-1 Integrase Inhibitors.Structure-Guided Optimization of HIV Integrase Strand Transfer Inhibitors.Application of oxime-diversification to optimize ligand interactions within a cryptic pocket of the polo-like kinase 1 polo-box domain.Correction to 4-Amino-1-hydroxy-2-oxo-1,8-naphthyridine-ContainingCompounds Having High Potency against Raltegravir-Resistant Integrase Mutants of HIV-1.Enhancing polo-like kinase 1 selectivity of polo-box domain-binding peptides.Developing and evaluating inhibitors against the RNase H active site of HIV-1 RT.Development of Highly Selective 1,2,3-Triazole-containing Peptidic Polo-like Kinase 1 Polo-box Domain-binding InhibitorsBiotinylated biphenyl ketone-containing 2,4-dioxobutanoic acids designed as HIV-1 integrase photoaffinity ligandsStructural basis for strand-transfer inhibitor binding to HIV intasomesIdentification of a ligand binding hot spot and structural motifs replicating aspects of tyrosyl-DNA phosphodiesterase I (TDP1) phosphoryl recognition by crystallographic fragment cocktail screening
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Q33862782-37D9D820-B3FC-4CCA-8A43-DBA5CD041BD8Q34080214-0B283A20-4DDB-4428-B1B6-B4EA140B609EQ34165394-51844BA6-0D23-4B54-8222-44D3E38EDCF5Q36812121-57AF9683-6508-48D2-A316-1A8499AB824AQ37281481-94C766A3-20AC-4A4C-9000-1F90DE58C3B6Q38565631-30FA7468-72DE-4538-8EA8-DA51994BA3E0Q41722020-4156A147-E266-4370-B72F-0EC8243E4029Q42383972-3B65C69F-9AA6-4F82-B9B7-331CCE9579F5Q45811620-D5DD3A05-2EB4-4571-BFEB-1A237EE3A5A5Q51101229-A1A699A6-EC4B-4242-8123-FFBE1CB24C87Q52593232-196CE3B2-5AF5-46E8-985F-E76EA527C116Q64253598-FC926CDD-1FF7-4033-B17B-A63D2E28A257Q80110193-8FDE9410-164C-459A-B973-231745A98001Q89453332-9576E1A0-F0BA-4BED-9330-5E73C8538F90Q92751916-81E65AAE-00D1-4F89-97C7-A99A764E3B0C
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description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Xue Zhi Zhao
@en
Xue Zhi Zhao
@nl
type
label
Xue Zhi Zhao
@en
Xue Zhi Zhao
@nl
prefLabel
Xue Zhi Zhao
@en
Xue Zhi Zhao
@nl
P31
P496
0000-0003-1006-6364