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Use of Adult Stem Cells for Cartilage Tissue Engineering: Current Status and Future DevelopmentsRegulation and Role of TGFβ Signaling Pathway in Aging and Osteoarthritis Joints3-Deazaneplanocin A (DZNep), an inhibitor of the histone methyltransferase EZH2, induces apoptosis and reduces cell migration in chondrosarcoma cells.Histone methylases as novel drug targets: developing inhibitors of EZH2.TOL19-001 reduces inflammation and MMP expression in monolayer cultures of tendon cellsHistone H3 Lysine 27 demethylases Jmjd3 and Utx are required for T-cell differentiationNFkappaB mediates IL-1beta-induced down-regulation of TbetaRII through the modulation of Sp3 expression.Anti-inflammatory and chondroprotective effects of the S-adenosylhomocysteine hydrolase inhibitor 3-Deazaneplanocin A, in human articular chondrocytes.Genetic Determinism of Primary Early-Onset Osteoarthritis.Identification of an easy to use 3D culture model to investigate invasion and anticancer drug response in chondrosarcomas.Asporin expression is highly regulated in human chondrocytes.Anti-inflammatory effects of an injectable copolymer of fatty acids (Ara 3000 beta®) in joint diseases.Hypoxia inducible factor 1 alpha down-regulates type i collagen through Sp3 transcription factor in human chondrocytes.Enhanced hyaline cartilage matrix synthesis in collagen sponge scaffolds by using siRNA to stabilize chondrocytes phenotype cultured with bone morphogenetic protein-2 under hypoxia.Interleukin-1beta up-regulation of Smad7 via NF-kappaB activation in human chondrocytes.Regulatory mechanism of transforming growth factor beta receptor type II degradation by interleukin-1 in primary chondrocytes.Evaluation of the impact of S-adenosylmethionine-dependent methyltransferase inhibitor, 3-deazaneplanocin A, on tissue injury and cognitive function in mice.Epigenetic dynamic during endochondral ossification and articular cartilage developmentModulation of Skin Inflammatory Response by Active Components of SilymarinChondroitin sulfate modulation of matrix and inflammatory gene expression in IL-1beta-stimulated chondrocytes--study in hypoxic alginate bead culturesInterleukin-1beta impairment of transforming growth factor beta1 signaling by down-regulation of transforming growth factor beta receptor type II and up-regulation of Smad7 in human articular chondrocytesThe Antitumoral Effect of the S-Adenosylhomocysteine Hydrolase Inhibitor, 3-Deazaneplanocin A, is Independent of EZH2 but is Correlated with EGFR Downregulation in ChondrosarcomasDevelopment of a simple osteoarthritis model useful to predict in vitro the anti-hypertrophic action of drugsAntiproliferative effect of the histone demethylase inhibitor GSK-J4 in chondrosarcomas
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investigador
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researcher
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wetenschapper
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C Baugé
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C Baugé
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C Baugé
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C Baugé
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C Baugé
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C Baugé
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0000-0001-5642-998X