about
STIM and Orai1 Variants in Store-Operated Calcium EntryThe STIM1/Orai signaling machineryEffect of homocysteine on calcium mobilization and platelet function in type 2 diabetes mellitus.Cinnamtannin B-1 as an antioxidant and platelet aggregation inhibitor.A calcium-accumulating region, CAR, in the channel Orai1 enhances Ca(2+) permeation and SOCE-induced gene transcription.Complex role of STIM1 in the activation of store-independent Orai1/3 channels.Cholesterol modulates Orai1 channel functionHomocysteine, intracellular signaling and thrombotic disorders.Role of oxidant scavengers in the prevention of Ca²+ homeostasis disorders.The TRPC ion channels: association with Orai1 and STIM1 proteins and participation in capacitative and non-capacitative calcium entry.Transient receptor potential channels in human platelets: expression and functional role.Homer proteins in Ca²⁺ entry.Regulators of G-protein-signaling proteins: negative modulators of G-protein-coupled receptor signaling.STIM and calcium channel complexes in cancer.Molecular mechanisms of STIM/Orai communication.Orai1 and Orai2 mediate store-operated calcium entry that regulates HL60 cell migration and FAK phosphorylation.The STIM1: Orai Interaction.Regulation of Platelet Function by Orai, STIM and TRP.Role of STIM2 in cell function and physiopathology.TRPs in Pain SensationDifferential involvement of thrombin receptors in Ca2+ release from two different intracellular stores in human platelets.Canonical transient receptor potential (TRPC) 1 acts as a negative regulator for vanilloid TRPV6-mediated Ca2+ influx.Store-operated Ca2+ entry is sensitive to the extracellular Ca2+ concentration through plasma membrane STIM1.Dynamic interaction of hTRPC6 with the Orai1-STIM1 complex or hTRPC3 mediates its role in capacitative or non-capacitative Ca(2+) entry pathways.Melatonin, as an adjuvant-like agent, enhances platelet responsiveness.Hydrogen peroxide and peroxynitrite enhance Ca2+ mobilization and aggregation in platelets from type 2 diabetic patients.The TRPV1 ion channel is expressed in human but not mouse platelets.Intracellular Ca2+ store depletion induces the formation of macromolecular complexes involving hTRPC1, hTRPC6, the type II IP3 receptor and SERCA3 in human platelets.Physical properties of two types of calcium stores and SERCAs in human platelets.Involvement of stanniocalcins in the deregulation of glycaemia in obese mice and type 2 diabetic patients.Filamin A Modulates Store-Operated Ca2+ Entry by Regulating STIM1 (Stromal Interaction Molecule 1)-Orai1 Association in Human Platelets.Fine-tuning of store-operated calcium entry by fast and slow Ca2+-dependent inactivation: Involvement of SARAF.Fine-tuning of microRNAs in type 2 diabetes mellitus.Apelin: an antithrombotic factor that inhibits platelet function.Flavonoids and platelet-derived thrombotic disorders.(-)‑Oleocanthal inhibits proliferation and migration by modulating Ca entry through TRPC6 in breast cancer cellsFilamin A modulates platelet functionTRPC6 Channels Are Required for Proliferation, Migration and Invasion of Breast Cancer Cell Lines by Modulation of Orai1 and Orai3 Surface ExposureStore-Operated Ca Entry in Breast Cancer Cells: Remodeling and Functional RoleEndogenously generated reactive oxygen species reduce PMCA activity in platelets from patients with non-insulin-dependent diabetes mellitus
P50
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P50
description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Isaac Jardín
@en
Isaac Jardín
@nl
type
label
Isaac Jardín
@en
Isaac Jardín
@nl
prefLabel
Isaac Jardín
@en
Isaac Jardín
@nl
P31
P496
0000-0003-4575-8264