about
Expression of Plasmodium falciparum erythrocyte membrane protein 1 in experimentally infected humansSub-grouping of Plasmodium falciparum 3D7 var genes based on sequence analysis of coding and non-coding regionsSurface co-expression of two different PfEMP1 antigens on single plasmodium falciparum-infected erythrocytes facilitates binding to ICAM1 and PECAM1PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparumSelective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malariaExpression of the domain cassette 8 Plasmodium falciparum erythrocyte membrane protein 1 is associated with cerebral malaria in BeninSerological evidence of discrete spatial clusters of Plasmodium falciparum parasitesPlasmodium falciparum Plasmodium helical interspersed subtelomeric proteins contribute to cytoadherence and anchor P. falciparum erythrocyte membrane protein 1 to the host cell cytoskeletonPlasmodium falciparum transcriptome analysis reveals pregnancy malaria associated gene expression.An upstream open reading frame controls translation of var2csa, a gene implicated in placental malaria.Multiple var2csa-type PfEMP1 genes located at different chromosomal loci occur in many Plasmodium falciparum isolatesPlasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes--divide and conquer.The role of EPCR in the pathogenesis of severe malariaIdentification of a major rif transcript common to gametocytes and sporozoites of Plasmodium falciparum.Antibodies against PfEMP1, RIFIN, MSP3 and GLURP are acquired during controlled Plasmodium falciparum malaria infections in naïve volunteers.Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children.Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian children.Severe malaria is associated with parasite binding to endothelial protein C receptorEvidence for the involvement of VAR2CSA in pregnancy-associated malaria.Structural conservation despite huge sequence diversity allows EPCR binding by the PfEMP1 family implicated in severe childhood malaria.Plasmodium falciparum var genes expressed in children with severe malaria encode CIDRα1 domains.The structural basis for CD36 binding by the malaria parasite.The Severity of Plasmodium falciparum Infection Is Associated with Transcript Levels of var Genes Encoding Endothelial Protein C Receptor-Binding P. falciparum Erythrocyte Membrane Protein 1.Differential expression of var gene groups is associated with morbidity caused by Plasmodium falciparum infection in Tanzanian children.Positive selection of Plasmodium falciparum parasites with multiple var2csa-type PfEMP1 genes during the course of infection in pregnant women.DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families.Immunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malaria.IgG antibodies to endothelial protein C receptor-binding cysteine-rich interdomain region domains of Plasmodium falciparum erythrocyte membrane protein 1 are acquired early in life in individuals exposed to malaria.Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasitesDifferences in PfEMP1s recognized by antibodies from patients with uncomplicated or severe malariaEvidence for in vitro and in vivo expression of the conserved VAR3 (type 3) plasmodium falciparum erythrocyte membrane protein 1.Cytoadhesion to gC1qR through Plasmodium falciparum Erythrocyte Membrane Protein 1 in Severe Malaria.Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania.Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes.Expression of a type B RIFIN in Plasmodium falciparum merozoites and gametes.Adhesion of Plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue: a novel model of placental malaria.The endothelial protein C receptor rs867186-GG genotype is associated with increased soluble EPCR and could mediate protection against severe malaria.Malaria's deadly grip: cytoadhesion of Plasmodium falciparum-infected erythrocytes.Cellulose filtration of blood from malaria patients for improving ex vivo growth of Plasmodium falciparum parasites.Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria.
P50
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P50
name
Thomas Lavstsen
@en
Thomas Lavstsen
@nl
type
label
Thomas Lavstsen
@en
Thomas Lavstsen
@nl
prefLabel
Thomas Lavstsen
@en
Thomas Lavstsen
@nl