about
An evolutionary method for learning HMM structure: prediction of protein secondary structureEBF2 determines and maintains brown adipocyte identityEBNA2 Drives Formation of New Chromosome Binding Sites and Target Genes for B-Cell Master Regulatory Transcription Factors RBP-jκ and EBF1Prdm16 is required for the maintenance of brown adipocyte identity and function in adult miceNonparametric Tests for Differential Histone Enrichment with ChIP-Seq Data.Prediction of regulatory elements in mammalian genomes using chromatin signatures.An integrated approach to identifying cis-regulatory modules in the human genome.Anti-diabetic rosiglitazone remodels the adipocyte transcriptome by redistributing transcription to PPARγ-driven enhancers.5-hydroxymethylcytosine represses the activity of enhancers in embryonic stem cells: a new epigenetic signature for gene regulationAkt-dependent metabolic reprogramming regulates tumor cell histone acetylationEbf2 is a selective marker of brown and beige adipogenic precursor cells.A wavelet approach to detect enriched regions and explore epigenomic landscapes.Zfp423 binds autoregulatory sites in p19 cell culture model.PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program.RBPJ, the major transcriptional effector of Notch signaling, remains associated with chromatin throughout mitosis, suggesting a role in mitotic bookmarking.The sequence-specific transcription factor c-Jun targets Cockayne syndrome protein B to regulate transcription and chromatin structure.Proteogenomics analysis reveals specific genomic orientations of distal regulatory regions composed by non-canonical histone variants.A stationary wavelet entropy-based clustering approach accurately predicts gene expressionGenomic redistribution of GR monomers and dimers mediates transcriptional response to exogenous glucocorticoid in vivo.Transcriptomic Profiling and H3K27me3 Distribution Reveal Both Demethylase-Dependent and Independent Regulation of Developmental Gene Transcription in Cell Differentiation.Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response In Vivo.ATF4 licenses C/EBPβ activity in human mesenchymal stem cells primed for adipogenesis.Histone H4 acetylation and the epigenetic reader Brd4 are critical regulators of pluripotency in embryonic stem cellsGlobal identification of transcriptional regulators of pluripotency and differentiation in embryonic stem cells.Prenatal Choline Supplementation Diminishes Early-Life Iron Deficiency-Induced Reprogramming of Molecular Networks Associated with Behavioral Abnormalities in the Adult Rat Hippocampus.The CSB chromatin remodeler and CTCF architectural protein cooperate in response to oxidative stress.The Nuclear Receptor Rev-erbα Regulates Adipose Tissue-specific FGF21 Signaling.An iPSC line from human pancreatic ductal adenocarcinoma undergoes early to invasive stages of pancreatic cancer progression.Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor.LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells.Epigenetic regulation of the DLK1-MEG3 microRNA cluster in human type 2 diabetic islets.Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasisA wavelet-based method to exploit epigenomic language in the regulatory region.Targeting PPARγ in the epigenome rescues genetic metabolic defects in mice.Modeling promoter grammars with evolving hidden Markov models.AMPK-SKP2-CARM1 signalling cascade in transcriptional regulation of autophagy.PRDM16 represses the type I interferon response in adipocytes to promote mitochondrial and thermogenic programing.Single-Cell Transcriptomics of the Human Endocrine Pancreas.Metazoan Nuclear Pores Provide a Scaffold for Poised Genes and Mediate Induced Enhancer-Promoter Contacts.Single cell transcriptomic profiling of mouse pancreatic progenitors.
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description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Kyoung-Jae Won
@en
Kyoung-Jae Won
@nl
type
label
Kyoung-Jae Won
@en
Kyoung-Jae Won
@nl
prefLabel
Kyoung-Jae Won
@en
Kyoung-Jae Won
@nl
P2456
P31
P496
0000-0002-2924-9630