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Evaluation of ursolic acid isolated from Ilex paraguariensis and derivatives on aromatase inhibitionDevelopment and validation of a bioanalytical method by LC-MS/MS for the quantification of the LAFIS 10 - an antimalarial candidate - and its pharmacokinetics first evaluation.Structural elucidation of gemifloxacin mesylate degradation product.Strategy of total synthesis based on the use of Rh-catalyzed stereoselective 1,4-addition.Design, Synthesis, and Biological Evaluation of Betulinic Acid Derivatives as New Antitumor Agents for Leukemia.Caatinga plants: Natural and semi-synthetic compounds potentially active against Trichomonas vaginalis.Quercetin derivative induces cell death in glioma cells by modulating NF-κB nuclear translocation and caspase-3 activation.Ursolic acid from apple pomace and traditional plants: A valuable triterpenoid with functional properties.Synthesis and antiplasmodial activity of betulinic acid and ursolic acid analogues.The inhibitory effects of phenolic and terpenoid compounds from Baccharis trimera in Siha cells: differences in their activity and mechanism of action.Two series of new semisynthetic triterpene derivatives: differences in anti-malarial activity, cytotoxicity and mechanism of action.Adenosine reduces reactive oxygen species and interleukin-8 production by Trichomonas vaginalis-stimulated neutrophils.Larvicidal activity of natural and modified triterpenoids against Aedes aegypti (Diptera: Culicidae).Standardized Passiflora incarnata L. Extract Reverts the Analgesia Induced by Alcohol Withdrawal in Rats.Synthesis and biological evaluation of hydrazone derivatives as antifungal agents.Quantification of saponins in extractive solution of mate leaves (Ilex paraguariensis A. St. Hil.).Improving the thrombin inhibitory activity of glycyrrhizin, a triterpenic saponin, through a molecular simplification of the carbohydrate moiety.Investigation of antimalarial activity, cytotoxicity and action mechanism of piperazine derivatives of betulinic acid.Triterpenoids from Brazilian Ilex species and their in vitro antitrypanosomal activity.Pharmacomodulation on the 3-acetylursolic acid skeleton: Design, synthesis, and biological evaluation of novel N-{3-[4-(3-aminopropyl)piperazinyl]propyl}-3-O-acetylursolamide derivatives as antimalarial agents.Semisynthesis, cytotoxicity, antimalarial evaluation and structure-activity relationship of two series of triterpene derivatives.Peptides as a strategy against biofilm-forming microorganisms: Structure-activity relationship perspectives.Synthesis of isosteric triterpenoid derivatives and antifungal activity.SERCA plays a crucial role in the toxicity of a betulinic acid derivative with potential antimalarial activity.Anti-Trichomonas vaginalis activity of ursolic acid derivative: a promising alternative.Promising Antibiofilm Activity of PeptidomimeticsAnti-Trichomonas vaginalis activity of saponins from Quillaja, Passiflora, and Ilex speciesAntithrombotic Effect of Chikusetsusaponin IVa Isolated from Ilex paraguariensis (Maté)Phenolic enriched extract of Baccharis trimera presents anti-inflammatory and antioxidant activitiesSynthesis and preliminary evaluation of new ursolic and oleanolic acids derivatives as antileishmanial agentsTriterpene Derivatives as Relevant Scaffold for New Antibiofilm DrugsIn vitro and in silico Activity of Iridoids Against Leishmania amazonensisA Highly Active Triterpene Derivative Capable |of Biofilm Damage to Control Cryptococcus sppBetulinic Acid and Brosimine B Hybrid Derivatives as Potential Agents against Female Cancers
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description
investigador
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researcher
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wetenschapper
@nl
name
Simone C B Gnoatto
@en
Simone C B Gnoatto
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type
label
Simone C B Gnoatto
@en
Simone C B Gnoatto
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prefLabel
Simone C B Gnoatto
@en
Simone C B Gnoatto
@nl
P31
P496
0000-0002-8806-3182