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Fucoxanthin and Its Metabolite Fucoxanthinol in Cancer Prevention and TreatmentMEF2 is restricted to the male gonad and regulates expression of the orphan nuclear receptor NR4A1Implications of leptin in neuroendocrine regulation of male reproduction.Implications of adiponectin in linking metabolism to testicular function.Roles of leptin, adiponectin and resistin in the transcriptional regulation of steroidogenic genes contributing to decreased Leydig cells function in obesity.Transcription factors SF1 and cJUN cooperate to activate the Fdx1 promoter in MA-10 Leydig cells.Cell interactions and genetic regulation that contribute to testicular Leydig cell development and differentiation.Expressions of Sox9, Sox5, and Sox13 transcription factors in mice testis during postnatal development.Adiponectin influences progesterone production from MA-10 Leydig cells in a dose-dependent manner.The nuclear receptor NR2F2 activates star expression and steroidogenesis in mouse MA-10 and MLTC-1 Leydig cells.Inhibitory effects of fucoxanthinol on the viability of human breast cancer cell lines MCF-7 and MDA-MB-231 are correlated with modulation of the NF-kappaB pathway.cAMP-induced expression of the orphan nuclear receptor Nur77 in MA-10 Leydig cells involves a CaMKI pathway.The human 3beta-hydroxysteroid dehydrogenase/Delta5-Delta4 isomerase type 2 promoter is a novel target for the immediate early orphan nuclear receptor Nur77 in steroidogenic cells.GATA factors and the nuclear receptors, steroidogenic factor 1/liver receptor homolog 1, are key mutual partners in the regulation of the human 3beta-hydroxysteroid dehydrogenase type 2 promoter.Cooperative regulation of Gja1 expression by members of the AP-1 family cJun and cFos in TM3 Leydig and TM4 Sertoli cells.Expression profiles of Sox transcription factors within the postnatal rodent testes.Steroidogenic genes expressions are repressed by high levels of leptin and the JAK/STAT signaling pathway in MA-10 Leydig cells.Influence of flavonols and quercetin derivative compounds on MA-10 Leydig cells steroidogenic genes expressions.Comparative effects between fucoxanthinol and its precursor fucoxanthin on viability and apoptosis of breast cancer cell lines MCF-7 and MDA-MB-231Gja1 expression is regulated by cooperation between SOX8/SOX9 and cJUN transcription factors in TM4 and 15P-1 Sertoli cell linesModulation of the transcriptomic profile of the R2C tumor Leydig cell line by the adipose tissue derived hormone leptinTranscriptomic analysis of overexpressed SOX4 and SOX8 in TM4 Sertoli cells with emphasis on cell-to-cell interactionsLuteolin modulates gene expression related to steroidogenesis, apoptosis, and stress response in rat LC540 tumor Leydig cellsRole of adiponectin as a modulator of testicular function during aging in mice
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description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Luc J Martin
@en
Luc J Martin
@nl
type
label
Luc J Martin
@en
Luc J Martin
@nl
prefLabel
Luc J Martin
@en
Luc J Martin
@nl
P31
P496
0000-0003-1919-8646