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Deficiency in Poly(ADP-ribose) Polymerase-1 (PARP-1) Accelerates Aging and Spontaneous Carcinogenesis in MiceIf started early in life, metformin treatment increases life span and postpones tumors in female SHR mice.Sex differences in aging, life span and spontaneous tumorigenesis in 129/Sv mice neonatally exposed to metformin.Effects of the mitochondria-targeted antioxidant SkQ1 on lifespan of rodents.Polyphenolic drug composition based on benzenepolycarboxylic acids (BP-C3) increases life span and inhibits spontaneous tumorigenesis in female SHR mice.Rodent models for the preclinical evaluation of drugs suitable for pharmacological intervention in aging.Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo.Metformin slows down aging and extends life span of female SHR mice.Biomarkers of aging, life span and spontaneous carcinogenesis in the wild type and HER-2 transgenic FVB/N female mice.
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description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Maria V Yurova
@en
Maria V Yurova
@nl
type
label
Maria V Yurova
@en
Maria V Yurova
@nl
prefLabel
Maria V Yurova
@en
Maria V Yurova
@nl
P31
P496
0000-0003-3589-5871