about
Novel roles in human MD-2 of phenylalanines 121 and 126 and tyrosine 131 in activation of Toll-like receptor 4 by endotoxin.Expression of functional D299G.T399I polymorphic variant of TLR4 depends more on coexpression of MD-2 than does wild-type TLR4.Functional activity of MD-2 polymorphic variant is significantly different in soluble and TLR4-bound forms: decreased endotoxin binding by G56R MD-2 and its rescue by TLR4 ectodomain.Transfer of monomeric endotoxin from MD-2 to CD14: characterization and functional consequences.Endotoxin-binding proteins modulate the susceptibility of bacterial endotoxin to deacylation by acyloxyacyl hydrolase.Specific high affinity interactions of monomeric endotoxin.protein complexes with Toll-like receptor 4 ectodomain.OmpR-dependent and OmpR-independent responses of Escherichia coli to sublethal attack by the neutrophil bactericidal/permeability increasing protein.
P50
Q38296779-8B5702FA-BFA1-4AFA-8CFA-ADE63E79EE80Q38345963-B61868F0-A162-4C06-8A58-DDE116C5F678Q39990387-F4A2A8FE-E8D1-499C-846A-070BD3FDC7B3Q40068424-4C4DBA21-2E6E-47A4-8936-64C194C606EBQ40182558-0763D249-0E56-4903-88F8-18AF34C00D4FQ40205438-9CEB9DC2-6D46-4475-A620-0816B6A39939Q52545858-BA03A912-13CA-44B5-9AED-1031874D3777
P50
name
Polonca Prohinar
@en
Polonca Prohinar
@nl
type
label
Polonca Prohinar
@en
Polonca Prohinar
@nl
prefLabel
Polonca Prohinar
@en
Polonca Prohinar
@nl