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A strategy to model nonmonotonic dose-response curve and estimate IC50Reduced fitness in cell culture of HIV-1 with nonnucleoside reverse transcriptase inhibitor-resistant mutations correlates with relative levels of reverse transcriptase content and RNase H activity in virions.Multi-Dimensional Measurement of Antibody-Mediated Heterosubtypic Immunity to Influenza.The HIV-1 reverse transcriptase mutants G190S and G190A, which confer resistance to non-nucleoside reverse transcriptase inhibitors, demonstrate reductions in RNase H activity and DNA synthesis from tRNA(Lys, 3) that correlate with reductions in repGraphical Representation of Proximity Measures for Multidimensional Data: Classical and Metric Multidimensional ScalingHIV vaccine could use a little help.L74V increases the reverse transcriptase content of HIV-1 virions with non-nucleoside reverse transcriptase drug-resistant mutations L100I+K103N and K101E+G190S, which results in increased fitness.Reverse transcriptase backbone can alter the polymerization and RNase activities of non-nucleoside reverse transcriptase mutants K101E+G190S.IL-15 enhances cross-reactive antibody recall responses to seasonal H3 influenza viruses in vitro.Broad cross-reactive IgG responses elicited by adjuvanted vaccination with recombinant influenza hemagglutinin (rHA) in ferrets and mice.A Highly Potent and Broadly Neutralizing H1 Influenza-Specific Human Monoclonal Antibody.Novel multiplex assay for profiling influenza antibodies in breast milk and serum of mother-infant pairsContinuous Readout versus Titer-Based Assays of Influenza Vaccine Trials: Sensitivity, Specificity, and False Discovery Rates.A Complex Dance: Measuring the Multidimensional Worlds of Influenza Virus Evolution and Anti-Influenza Immune ResponsesBroad Hemagglutinin-Specific Memory B Cell Expansion by Seasonal Influenza Virus Infection Reflects Early-Life Imprinting and Adaptation to the Infecting VirusApplication of volumetric absorptive microsampling (VAMS) to measure multidimensional anti-influenza IgG antibodies by the mPlex-Flu assayThe adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypesImproved Specificity and False Discovery Rates for Multiplex Analysis of Changes in Strain-Specific Anti-Influenza IgG
P50
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P50
description
researcher (ORCID 0000-0002-4938-5074)
@en
name
J Wang
@en
type
label
J Wang
@en
prefLabel
J Wang
@en
P31
P496
0000-0002-4938-5074