about
Grb7 upregulation is a molecular adaptation to HER2 signaling inhibition due to removal of Akt-mediated gene repressionEIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibitionNicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activityFasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition.Synthetic lethality-based therapeutics: perspectives for applications in colorectal cancer.Nicotinamide phosphoribosyltransferase (NAMPT) inhibitors as therapeutics: rationales, controversies, clinical experience.APO866 Increases Antitumor Activity of Cyclosporin-A by Inducing Mitochondrial and Endoplasmic Reticulum Stress in Leukemia Cells.Dynamic simulations of pathways downstream of ERBB-family, including mutations and treatments: concordance with experimental results.Depletion of SIRT6 enzymatic activity increases acute myeloid leukemia cells' vulnerability to DNA-damaging agents.Dual NAMPT and BTK Targeting Leads to Synergistic Killing of Waldenström Macroglobulinemia Cells Regardless of MYD88 and CXCR4 Somatic Mutation Status.SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects.Exploiting tumor vulnerabilities: NAD(+)-depleting agents combined with anti-tumor drugs as innovative strategy to treat hematological malignancies.Synthesis and biological characterization of 3-(imidazol-1-ylmethyl)piperidine sulfonamides as aromatase inhibitorsTreatment with Angiotensin-(1–7) reduces inflammation in carotid atherosclerotic plaquesLong non-coding RNA NEAT1 targeting impairs the DNA repair machinery and triggers anti-tumor activity in multiple myeloma
P50
Q33528957-4B7FA1AD-6DB2-4EA9-A508-E789DE967E65Q34500782-C01B8CD9-39E2-45B1-AF09-DE763EEAF82AQ34634272-EBD36B20-B95E-4964-AB79-56F61BEAA8DCQ35828447-47676A85-7301-40A5-97FF-AC86D7977E74Q37990056-04D46A2C-D49F-45A2-8F81-C5F1CAB2681BQ38093300-38F457FE-C2C0-4007-AD88-E4550A95E741Q38876222-67ACB5F3-AE4A-4B6B-AA14-0E2620A321DAQ39688255-BE2A9552-42C5-4E51-A832-54683B951BC0Q47808353-9B9F617D-43D6-461C-A5DA-DA7B4CF0A1EDQ49372280-EE07771D-2219-406E-B08A-A4C088DB0587Q49662561-25AAC617-0805-484E-9AF5-B7DBF0E3FB3BQ50782958-28646314-F6E1-4DFC-9A1B-399F7205BCB4Q56964405-77015B6A-B0AB-478D-B0D9-697692F99C25Q58197608-429D768C-7215-4EFA-9470-FF0A582E5105Q92710248-0B59CB77-8889-4909-B54F-E54313C0B6C4
P50
description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Debora Soncini
@en
Debora Soncini
@nl
type
label
Debora Soncini
@en
Debora Soncini
@nl
prefLabel
Debora Soncini
@en
Debora Soncini
@nl
P31
P496
0000-0001-5156-498X