about
Periplasmic adaptor protein AcrA has a distinct role in the antibiotic resistance and virulence of Salmonella enterica serovar Typhimurium.Lack of AcrB Efflux Function Confers Loss of Virulence on Salmonella enterica Serovar Typhimurium.Choice of bacterial growth medium alters the transcriptome and phenotype of Salmonella enterica Serovar TyphimuriumRedundancy in the periplasmic adaptor proteins AcrA and AcrE provides resilience and an ability to export substrates of multidrug efflux.AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity.Epidemiological evidence for the role of the hemoglobin receptor, hmbR, in meningococcal virulence.Structure, function and inhibition of RND efflux pumps in Gram-negative bacteria: an update.Multidrug efflux pumps in Gram-negative bacteria and their role in antibiotic resistance.Molecular mechanisms of antibiotic resistance.How to Measure Export via Bacterial Multidrug Resistance Efflux PumpsBeyond Antimicrobial Resistance: Evidence for a Distinct Role of the AcrD Efflux Pump in Salmonella Biology.The global consequence of disruption of the AcrAB-TolC efflux pump in Salmonella enterica includes reduced expression of SPI-1 and other attributes required to infect the host.Expression of homologous RND efflux pump genes is dependent upon AcrB expression: implications for efflux and virulence inhibitor design.RamA, which controls expression of the MDR efflux pump AcrAB-TolC, is regulated by the Lon proteaseAlternative explanation for indole-induced antibiotic tolerance in Salmonella.RND efflux pumps in Gram-negative bacteria; regulation, structure and role in antibiotic resistanceTetR-family transcription factors in Gram-negative bacteria: conservation, variation and implications for efflux-mediated antimicrobial resistanceIdentification of binding residues between periplasmic adapter protein (PAP) and RND efflux pumps explains PAP-pump promiscuity and roles in antimicrobial resistanceBiofilm Eradication by Symmetrical Selenoesters for Food-Borne Pathogens
P50
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P50
description
investigador
@es
researcher
@en
name
Jessica M A Blair
@en
type
label
Jessica M A Blair
@en
prefLabel
Jessica M A Blair
@en
P31
P496
0000-0001-6904-4253