about
Discovery of butyrylcholinesterase inhibitors among derivatives of azaphenothiazines.Application of computational methods for the design of BACE-1 inhibitors: validation of in silico modelling.Therapeutic strategies for Alzheimer's disease in clinical trials.Hybrid approach to structure modeling of the histamine H3 receptor: Multi-level assessment as a tool for model verificationNew tacrine analogs as acetylcholinesterase inhibitors - theoretical study with chemometric analysis.New cyclopentaquinoline hybrids with multifunctional capacities for the treatment of Alzheimer's disease.Design, Synthesis, and Biological Evaluation of 1-Benzylamino-2-hydroxyalkyl Derivatives as New Potential Disease-Modifying Multifunctional Anti-Alzheimer's Agents.Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation.Cholinesterase inhibitory activity of chlorophenoxy derivatives-Histamine H3 receptor ligands.Tetrahydroacridine derivatives with dichloronicotinic acid moiety as attractive, multipotent agents for Alzheimer's disease treatment.Design, Synthesis, and Biological Evaluation of 2-(Benzylamino-2-Hydroxyalkyl)Isoindoline-1,3-Diones Derivatives as Potential Disease-Modifying Multifunctional Anti-Alzheimer Agents.Tetrahydroacridine derivatives with fluorobenzoic acid moiety as multifunctional agents for Alzheimer's disease treatment.Novel carbamate derivatives as selective butyrylcholinesterase inhibitors.Synthesis, biological evaluation and molecular modeling of new tetrahydroacridine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.Discovery of New Cyclopentaquinoline Analogues as Multifunctional Agents for the Treatment of Alzheimer's DiseaseDual-acting diether derivatives of piperidine and homopiperidine with histamine H(3) receptor antagonistic and anticholinesterase activityDesign and synthesis of new barbituric- and thiobarbituric acid derivatives as potent urease inhibitors: Structure activity relationship and molecular modeling studiesNovel biphenyl bis-sulfonamides as acetyl and butyrylcholinesterase inhibitors: Synthesis, biological evaluation and molecular modeling studiesSearch for multifunctional agents against Alzheimer's disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivativesCharacteristics of metabolic stability and the cell permeability of 2-pyrimidinyl-piperazinyl-alkyl derivatives of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione with antidepressant- and anxiolytic-like activitiesNew Tetrahydroacridine Hybrids with Dichlorobenzoic Acid Moiety Demonstrating Multifunctional Potential for the Treatment of Alzheimer's Disease
P50
Q35130541-8091D80A-F7E1-4F93-9F89-C5632147D4D8Q37684153-9EDF4FD9-7842-4D51-8F51-7224703A0736Q38684338-1773C228-2A20-43BF-A379-DAC08A3C2199Q42370925-921C4A4B-B768-4211-B0A4-957B6C31FC46Q45815071-C72632CA-F938-4A58-82CC-27B2ADDDC400Q47324891-75D70488-0CD0-4DBB-B97D-03244CA65074Q48219332-9DDF2BFE-FA36-4BAF-AF7F-C4BB4D0B586DQ48483594-E8DD52BE-99F7-4AC1-B8E6-B992803D2CE6Q49162475-8936E6B4-2171-4EBC-A6C5-CF2C6B8B6FE1Q49895777-37B417F9-CDCC-48FC-958A-67169F12ED6BQ50133770-D00EC06A-98F1-499F-913E-6A15B3133681Q51003552-4683621C-2936-4045-A633-3EEC8E308044Q52660490-9982FB04-6EBF-41C6-9598-4898921ACC0BQ53366910-52D64D41-932E-4A68-843E-18A06C7E2CEDQ64274407-8A12EE6F-7D55-46D4-9286-825A92237591Q84052036-980ACC01-F344-4ECC-ACAB-92FBFED49AEEQ85392008-0DDE4ACA-FC9F-4568-A015-834CC1E27966Q86766120-009D376A-C898-46A9-ABF3-3F4ADE52F54AQ91609483-DE745A12-E44F-43DE-8E97-2248EAC43035Q93031823-00FE385F-687C-4111-A39D-6FCD94F67597Q95932151-427F186F-7D2D-4D87-A28B-B0B31036F2D9
P50
description
investigador
@es
researcher
@en
name
Jakub Jończyk
@en
type
label
Jakub Jończyk
@en
prefLabel
Jakub Jończyk
@en
P31
P496
0000-0002-9731-908X