about
Expression quantitative trait loci are highly sensitive to cellular differentiation stateEpigenetic perturbations in aging stem cellsTracing dynamics and clonal heterogeneity of Cbx7-induced leukemic stem cells by cellular barcoding.Barcoded vector libraries and retroviral or lentiviral barcoding of hematopoietic stem cells.Development of a diverse human T-cell repertoire despite stringent restriction of hematopoietic clonality in the thymus.Long-Term In Vitro Expansion of Salivary Gland Stem Cells Driven by Wnt SignalsAsymmetry in skeletal distribution of mouse hematopoietic stem cell clones and their equilibration by mobilizing cytokines.Hematopoietic stem cell expansion: challenges and opportunities.microRNAs in hematopoiesis.Clonal heterogeneity as a driver of disease variability in the evolution of myeloproliferative neoplasms.Shared Ageing Research Models (ShARM): a new facility to support ageing research.Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions.Clonal selection and asymmetric distribution of human leukemia in murine xenografts revealed by cellular barcoding.Hematopoiesis during development, aging, and disease.Similar ex vivo expansion and post-irradiation regenerative potential of juvenile and aged salivary gland stem cells.Undifferentiated embryonic cell transcription factor 1 regulates ESC chromatin organization and gene expression.Human Salivary Gland Stem Cells Functionally Restore Radiation Damaged Salivary Glands.Inferring combinatorial association logic networks in multimodal genome-wide screens.Purification and ex vivo expansion of fully functional salivary gland stem cells.Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation.Noncanonical Wnt comes of age in hematopoietic stem cells.Counting stem cells: methodological constraints.Loss of Tcf7 diminishes hematopoietic stem/progenitor cell function.Priming of microglia in a DNA-repair deficient model of accelerated aging.Lifelong dietary intervention does not affect hematopoietic stem cell function.MicroRNA-125 family members exert a similar role in the regulation of murine hematopoiesis.Do hematopoietic stem cells get old?Heterogeneity of young and aged murine hematopoietic stem cells revealed by quantitative clonal analysis using cellular barcoding.Left or right? Directions to stem cell engraftment.Aging of hematopoietic stem cells.Memory CD8+ T cells support the maintenance of hematopoietic stem cells in the bone marrow.Stem Cells and Aging: What's Next?CITED2-mediated human hematopoietic stem cell maintenance is critical for acute myeloid leukemia.Epigenetic age-predictor for mice based on three CpG sitesMiR-125a enhances self-renewal, lifespan, and migration of murine hematopoietic stem and progenitor cell clonesC/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice.Repression of BMI1 in normal and leukemic human CD34(+) cells impairs self-renewal and induces apoptosisEngraftment of syngeneic bone marrow is not more efficient after intrafemoral transplantation than after traditional intravenous administrationSca-1 is an early-response target of histone deacetylase inhibitors and marks hematopoietic cells with enhanced functionCBX7 Induces Self-Renewal of Human Normal and Malignant Hematopoietic Stem and Progenitor Cells by Canonical and Non-canonical Interactions
P50
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P50
description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Gerald de Haan
@en
Gerald de Haan
@nl
type
label
Gerald de Haan
@en
Gerald de Haan
@nl
prefLabel
Gerald de Haan
@en
Gerald de Haan
@nl
P31
P496
0000-0001-9706-0138