about
Polycomb PHF19 binds H3K36me3 and recruits PRC2 and demethylase NO66 to embryonic stem cell genes during differentiationA chromatin-independent role of Polycomb-like 1 to stabilize p53 and promote cellular quiescence.Exploiting the Epigenome to Control Cancer-Promoting Gene-Expression Programs.Transcriptomics: unravelling the biology of transcription factors and chromatin remodelers during development and differentiation.Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent CellsNUP98 Fusion Proteins Interact with the NSL and MLL1 Complexes to Drive Leukemogenesis.The PCL1-p53 axis promotes cellular quiescence.Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands.Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcomaTargeting chromatin complexes in fusion protein-driven malignancies
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Q24304060-25295B45-EF26-40E5-9560-1D5D17B545E7Q36286764-ED49E962-DC60-4B51-91F0-8C042130D6DDQ36956610-92D4F701-960B-49FA-A92B-AE630F29F18EQ37580119-7EA00A6D-66E4-4D9A-AB2D-E64B05FF9906Q38734339-81C8BF58-FF7B-4E76-967E-BB37A9706AC4Q39152206-EE0C5791-DA13-4EA9-9F57-402907CB8D4BQ42423459-505E6D5C-076E-4C5F-BD05-9B9B44B6D882Q48265414-FBE6DE7C-A45B-4334-8C09-70DDC99DF477Q59800754-97669C74-B700-4500-BF4C-FB9FC83F0CDDQ92955229-A6B2E41A-D88A-4B0C-8029-EB21C8094FD4
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description
investigador
@es
researcher
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name
Gerard L Brien
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type
label
Gerard L Brien
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prefLabel
Gerard L Brien
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P108
P108
P31
P496
0000-0003-4275-7178