about
Adenosine A(2A) receptors promote collagen production by a Fli1- and CTGF-mediated mechanism.α1D-Adrenoceptors are responsible for the high sensitivity and the slow time-course of noradrenaline-mediated contraction in conductance arteries.Activation of EPAC1/2 is essential for osteoclast formation by modulating NFκB nuclear translocation and actin cytoskeleton rearrangementsDifferences in the signaling pathways of α(1A)- and α(1B)-adrenoceptors are related to different endosomal targetingDirect or indirect stimulation of adenosine A2A receptors enhances bone regeneration as well as bone morphogenetic protein-2.Brief Report: Methotrexate Prevents Wear Particle-Induced Inflammatory Osteolysis in Mice Via Activation of Adenosine A2A Receptor.Apremilast, a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors.Adenosine A2A receptor plays an important role in radiation-induced dermal injuryAdenosine A2A receptor and TNF-α regulate the circadian machinery of the human monocytic THP-1 cells.Activation of adenosine A(2A) receptor reduces osteoclast formation via PKA- and ERK1/2-mediated suppression of NFκB nuclear translocationAdenosine A2A receptor (A2AR) is a fine-tune regulator of the collagen1:collagen3 balanceAdenosine 2A receptor promotes collagen production by human fibroblasts via pathways involving cyclic AMP and AKT but independent of Smad2/3.Extracellular generation of adenosine by the ectonucleotidases CD39 and CD73 promotes dermal fibrosis.Different β-adrenoceptor subtypes coupling to cAMP or NO/cGMP pathways: implications in the relaxant response of rat conductance and resistance vessels.Adenosine A2A receptor promotes collagen type III synthesis via β-catenin activation in human dermal fibroblasts.The antiviral drug tenofovir, an inhibitor of Pannexin-1-mediated ATP release, prevents liver and skin fibrosis by downregulating adenosine levels in the liver and skin.β-Adrenoceptors differentially regulate vascular tone and angiogenesis of rat aorta via ERK1/2 and p38.Striae reconstructed, a full thickness skin model that recapitulates the pathology behind stretch marks
P50
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P50
description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Miguel Perez-Aso
@en
Miguel Perez-Aso
@nl
type
label
Miguel Perez-Aso
@en
Miguel Perez-Aso
@nl
prefLabel
Miguel Perez-Aso
@en
Miguel Perez-Aso
@nl
P31
P496
0000-0002-4703-4182