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Recent Advances in Understanding of Kinetic Interplay Between Phase II Metabolism and Efflux Transport.Glucose-Based Mesoporous Carbon Nanospheres as Functional Carriers for Oral Delivery of Amphiphobic Raloxifene: Insights into the Bioavailability Enhancement and Lymphatic Transport.In vitro characterization of belinostat glucuronidation: demonstration of both UGT1A1 and UGT2B7 as the main contributing isozymes.Simultaneous quantification of six alkaloid components from commercial stemonae radix by solid phase extraction-high-performance liquid chromatography coupled with evaporative light scattering detector.N-glucuronidation catalyzed by UGT1A4 and UGT2B10 in human liver microsomes: Assay optimization and substrate identification.Identification of UDP-glucuronosyltransferases 1A1, 1A3 and 2B15 as the main contributors to glucuronidation of bakuchiol, a natural biologically active compound.Metabolism of the anthelmintic drug niclosamide by cytochrome P450 enzymes and UDP-glucuronosyltransferases: metabolite elucidation and main contributions from CYP1A2 and UGT1A1.REV-ERBa Regulates CYP7A1 through Repression of Liver Receptor Homolog-1.Farnesoid X receptor regulates SULT1E1 expression through inhibition of PGC1α binding to HNF4α.Transcriptional Regulation of Human UDP-Glucuronosyltransferase 2B10 by Farnesoid X Receptor in Human Hepatoma HepG2 Cells.Cremophor EL-based nanoemulsion enhances transcellular permeation of emodin through glucuronidation reduction in UGT1A1-overexpressing MDCKII cells.Structure- and isoform-specific glucuronidation of six curcumin analogs.Multidrug Resistance-Associated Protein 4 (MRP4/ABCC4) Controls Efflux Transport of Hesperetin Sulfates in Sulfotransferase 1A3-Overexpressing Human Embryonic Kidney 293 Cells.Regio- and isoform-specific glucuronidation of psoralidin: evaluation of 3-o-glucuronidation as a functional marker for UGT1A9.Metabolism elucidation of BJ-B11 (a heat shock protein 90 inhibitor) by human liver microsomes: identification of main contributing enzymes.Identification of glucuronidation and biliary excretion as the main mechanisms for gossypol clearance: in vivo and in vitro evidenceQuantitative analysis of Cistanches Herba using high-performance liquid chromatography coupled with diode array detection and high-resolution mass spectrometry combined with chemometric methodsDisposition of Mianserin and Cyclizine in UGT2B10-Overexpressing Human Embryonic Kidney 293 Cells: Identification of UGT2B10 as a Novel N-Glucosidation Enzyme and Breast Cancer Resistance Protein as an N-Glucoside TransporterCircadian clock-controlled drug metabolism: Implications for chronotherapeuticsHighly selective N-glucuronidation of four piperazine-containing drugs by UDP-glucuronosyltransferase 2B10Circadian clock regulates hepatotoxicity of Tripterygium wilfordii through modulation of metabolism
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description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Danyi Lu
@en
Danyi Lu
@nl
type
label
Danyi Lu
@en
Danyi Lu
@nl
prefLabel
Danyi Lu
@en
Danyi Lu
@nl
P108
P31
P496
0000-0002-3346-2362