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Inhibition of de novo NAD(+) synthesis by oncogenic URI causes liver tumorigenesis through DNA damageTerminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2Inflammation-mediated skin tumorigenesis induced by epidermal c-Fos.Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expressionLoss of JUNB/AP-1 promotes invasive prostate cancerOsteogenic capillaries orchestrate growth plate-independent ossification of the malleus.JUNB/AP-1 controls IFN-γ during inflammatory liver disease.Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress.Mouse models for liver cancer.Characterization of mouse model-derived osteosarcoma (OS) cells in vitro and in vivo.Hepatitis C virus core+1/ARF protein decreases hepcidin transcription through an AP1 binding site.Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulationA FATal AP-1 dimer switch in hepatosteatosis.Activator Protein 1 transcription factor Fos-related antigen 1 (Fra-1) is dispensable for murine liver fibrosis, but modulates xenobiotic metabolism.News and views on EMT Fra-1 controls EMT in mammary epithelial cells.Fra-2 negatively regulates postnatal alveolar septation by modulating myofibroblast function.Transcriptional regulation by NR5A2 links differentiation and inflammation in the pancreas.The AP-1 transcription factor JunB is essential for multiple myeloma cell proliferation and drug resistance in the bone marrow microenvironment.EGFR controls bone development by negatively regulating mTOR-signaling during osteoblast differentiation.Virus Delivery of CRISPR Guides to the Murine Prostate for Gene AlterationOsteoblast-specific expression of Fra-2/AP-1 controls adiponectin and osteocalcin expression and affects metabolismEGFR is required for FOS-dependent bone tumor development via RSK2/CREB signalingFra-2-expressing macrophages promote lung fibrosis in mice
P50
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P50
description
investigador
@es
researcher
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wetenschapper
@nl
name
L Bakiri
@en
L Bakiri
@nl
type
label
L Bakiri
@en
L Bakiri
@nl
prefLabel
L Bakiri
@en
L Bakiri
@nl
P31
P496
0000-0002-6300-2420