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Development of a Novel AAV Gene Therapy Cassette with Improved Safety Features and Efficacy in a Mouse Model of Rett SyndromeImproved MECP2 Gene Therapy Extends the Survival of MeCP2-Null Mice without Apparent Toxicity after Intracisternal Delivery.Gait analysis in a Mecp2 knockout mouse model of Rett syndrome reveals early-onset and progressive motor deficitsLabel-free imaging of thick tissue at 1550 nm using a femtosecond optical parametric generator.Improved survival and reduced phenotypic severity following AAV9/MECP2 gene transfer to neonatal and juvenile male Mecp2 knockout mice.Reduced axonal diameter of peripheral nerve fibers in a mouse model of Rett syndrome.Radically truncated MeCP2 rescues Rett syndrome-like neurological defects.Toxic effect of aflatoxin B1 and the role of recovery on the rat cerebral cortex and hippocampus.Inhibition of Piezo1 attenuates demyelination in the central nervous system
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Q33652467-D686BD51-8E4C-402B-8772-0588338115B9Q33655727-D81D4541-446C-4557-AA13-635EC81B2596Q34506454-6167FB70-6A48-4984-ADB7-D8DAF7AE8BA5Q35741157-6D6F5F9F-6F41-4B47-8C53-0B35167F8450Q36507871-3C5D3C32-3C5D-47DB-BE63-27E36E5D1ADCQ40143992-4760CD33-806E-4FBF-B3A4-5BB5F0FB6691Q41919307-37F0693A-A4F7-47E3-ABD1-902E59517B47Q50982538-E2BBECF6-0D54-4B4E-978B-AFDB219E4517Q90608717-064C8087-53CB-4A54-8415-6698F2D66643
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description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Kamal K E Gadalla
@en
Kamal K E Gadalla
@nl
type
label
Kamal K E Gadalla
@en
Kamal K E Gadalla
@nl
prefLabel
Kamal K E Gadalla
@en
Kamal K E Gadalla
@nl
P31
P496
0000-0002-1657-8953