about
Small molecule inhibits activity of scavenger receptor A: Lead identification and preliminary studiesStructure-Based Discovery of New Antagonist and Biased Agonist Chemotypes for the Kappa Opioid ReceptorDesign, synthesis, and biological evaluation of 14-heteroaromatic-substituted naltrexone derivatives: pharmacological profile switch from mu opioid receptor selectivity to mu/kappa opioid receptor dual selectivityDesign, syntheses, and pharmacological characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan analogues as opioid receptor ligandsBinding mode characterization of 6α- and 6β-N-heterocyclic substituted naltrexamine derivatives via docking in opioid receptor crystal structures and site-directed mutagenesis studies: application of the 'message-address' concept in development of m17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-(4'-pyridylcarboxamido)morphinan (NAP) Modulating the Mu Opioid Receptor in a Biased Fashion6β-N-Heterocyclic Substituted Naltrexamine Derivative BNAP: A Peripherally Selective Mixed MOR/KOR Ligand.5-Hydroxy-2-(2-phenylethyl)chromone (5-HPEC): a novel non-nitrogenous ligand for 5-HT2B receptor.Structural insight into the activation of a class B G-protein-coupled receptor by peptide hormones in live human cells.Binding mode analyses of NAP derivatives as mu opioid receptor selective ligands through docking studies and molecular dynamics simulation.Exploration on natural product anibamine side chain modification toward development of novel CCR5 antagonists and potential anti-prostate cancer agents.Design, syntheses, and characterization of pharmacophore based chemokine receptor CCR5 antagonists as anti prostate cancer agents.Synthesis and Characterization of 5-Hydroxy-2-(2-phenylethyl)chromone (5-HPEC) and Its Analogues as Non-nitrogenous 5-HT2B Ligands.Understanding molecular interactions between scavenger receptor A and its natural product inhibitors through molecular modeling studies.Dynamic Strategic Bond Analysis Yields a Ten-Step Synthesis of 20-nor-Salvinorin A, a Potent κ-OR Agonist.Intracellular Transfer of Na+ in an Active-State G-Protein-Coupled Receptor.Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor.Crystal structure of the Frizzled 4 receptor in a ligand-free state
P50
Q28397940-D8315CF6-CD5E-4741-9256-B9C176B86F9DQ33860286-CBE8E2BF-218E-4598-98E8-6E40981E86D2Q35216655-E20C725B-9870-418D-B281-E518581C9EA2Q35236118-293F49AE-81AC-4320-9F13-809C30BA58B1Q37317909-D09D80BB-056B-4326-9053-FF9F07A0D75DQ37417284-646AAD4F-9EFC-48D5-B4EE-00C830E4E0CBQ37444418-9559A085-0019-449A-9EA8-3639C4677E2DQ37730936-A487E203-33E3-40AA-8AED-C158CAF514CFQ38644545-5594DFC6-7165-4BE7-B51C-FF5B8DC16FADQ38743944-A6E12559-62DD-4119-82F1-2414DCAF88F5Q38861474-754B5B07-D4BB-4608-B8CE-9B0608B63748Q39085948-3A8C4ECA-37E7-481A-9567-E2743E6C3658Q45017683-6E46DE34-D05A-4E6D-8AE7-FE5D923A615BQ45066494-CAE85810-77F0-49F4-A63B-30A929A47863Q47142355-1511F691-2AE0-499D-A556-9AD54EF2429FQ47241989-BEF6850D-5529-4379-9858-F5FCA270E29FQ47558272-C45D69C0-7868-4276-863B-95B08C10F1B4Q57830727-DCBB0E68-722A-46E6-B126-5D187B65CE02
P50
description
investigador
@es
researcher
@en
wetenschapper
@nl
name
Saheem A Zaidi
@en
Saheem A Zaidi
@nl
type
label
Saheem A Zaidi
@en
Saheem A Zaidi
@nl
prefLabel
Saheem A Zaidi
@en
Saheem A Zaidi
@nl
P31
P496
0000-0001-7531-3587